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    CXE12 alpha/beta-Hydrolases superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824030, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CXE12
    Official Full Name
    alpha/beta-Hydrolases superfamily protein
    Primary source
    TAIR:AT3G48690
    Locus tag
    AT3G48690
    See related
    Araport:AT3G48690
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA CARBOXYESTERASE 12; ATCXE12
    Summary
    Encodes a protein with carboxylesterase whose activity was tested using both pNA and 2,4-D-methyl.
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    Genomic context

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    See CXE12 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    1
    Sequence:
    Chromosome: 3; NC_003074.8 (18037046..18038234, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene egg cell-secreted-like protein (DUF1278) Neighboring gene gamma carbonic anhydrase-like 2 Neighboring gene carboxyesterase 13 Neighboring gene DEK domain-containing chromatin associated protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Role of a carboxylesterase in herbicide bioactivation in Arabidopsis thaliana. Gershater MC, et al. J Biol Chem, 2007 Jul 20. PMID 17519238
    2. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    • At3g48690_Arabidopsis_lyrata_ssp._lyrata_CAN1 (e-PCR)
    • At3g48690_Arabidopsis_lyrata_ssp._petraea_GER1 (e-PCR)
    NM_114728.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables carboxylesterase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables carboxylesterase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in cytosol HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    alpha/beta-Hydrolases superfamily protein
    NP_190438.1
    • CXE12; FUNCTIONS IN: carboxylesterase activity; INVOLVED IN: response to salt stress; LOCATED IN: cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Lipase, GDXG, active site (InterPro:IPR002168), Alpha/beta hydrolase fold-3 (InterPro:IPR013094); BEST Arabidopsis thaliana protein match is: carboxyesterase 13 (TAIR:AT3G48700.1); Has 9324 Blast hits to 9298 proteins in 1467 species: Archae - 108; Bacteria - 5259; Metazoa - 789; Fungi - 845; Plants - 1410; Viruses - 3; Other Eukaryotes - 910 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      18037046..18038234 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114728.5 → NP_190438.1  alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190438.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WVA6, Q8VZG3, Q9SMN0
      UniProtKB/TrEMBL
      A0A178V6D2, A0A5S9XJ56
      Conserved Domains (2) summary
      COG0657
      Location:11 → 321
      Aes; Acetyl esterase/lipase [Lipid transport and metabolism]
      pfam07859
      Location:74 → 282
      Abhydrolase_3; alpha/beta hydrolase fold
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SMN0.1

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