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    NAC053 NAC domain containing protein 53 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 820214, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NAC053
    Official Full Name
    NAC domain containing protein 53
    Primary source
    TAIR:AT3G10500
    Locus tag
    AT3G10500
    See related
    Araport:AT3G10500
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AIF; anac053; ANAC053; ANTHER INDEHISCENCE FACTOR; NAC domain containing protein 53; NAC with transmembrane motif 1-like 4; NTL4
    Summary
    Encodes a transcriptional activator that is associated with the plasma membrane in a dormant form and is proteolytically cleaved to create a form that can enter the nucleus. It is thought to promote ROS production by binding directly to the promoters of genes encoding ROS biosynthetic enzymes during drought-induced leaf senescence.
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    Genomic context

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    See NAC053 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (3271217..3274176)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene NAC domain containing protein 50 Neighboring gene NAC domain containing protein 52 Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene hemoglobin 2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The NAC-like gene ANTHER INDEHISCENCE FACTOR acts as a repressor that controls anther dehiscence by regulating genes in the jasmonate biosynthesis pathway in Arabidopsis. Shih CF, et al. J Exp Bot, 2014 Feb. PMID 24323506, Free PMC Article
    2. A NAC transcription factor NTL4 promotes reactive oxygen species production during drought-induced leaf senescence in Arabidopsis. Lee S, et al. Plant J, 2012 Jun. PMID 22313226
    3. A subcellular localization compendium of hydrogen peroxide-induced proteins. Inzé A, et al. Plant Cell Environ, 2012 Feb. PMID 21443605
    4. Establishment of Expression in the SHORTROOT-SCARECROW Transcriptional Cascade through Opposing Activities of Both Activators and Repressors. Sparks EE, et al. Dev Cell, 2016 Dec 5. PMID 27923776, Free PMC Article
    5. Promoter-based integration in plant defense regulation. Li B, et al. Plant Physiol, 2014 Dec. PMID 25352272, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The present data suggest a role for AIF in controlling anther dehiscence by suppressing the expression of jasmonic acid biosynthesis genes in Arabidopsis.[AIF]
      Title: The NAC-like gene ANTHER INDEHISCENCE FACTOR acts as a repressor that controls anther dehiscence by regulating genes in the jasmonate biosynthesis pathway in Arabidopsis.
    2. NTL4 acts as a molecular switch that couples ROS metabolism to drought-induced leaf senescence.
      Title: A NAC transcription factor NTL4 promotes reactive oxygen species production during drought-induced leaf senescence in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    NM_111885.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables transcription cis-regulatory region binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within drought recovery IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf senescence IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of reactive oxygen species metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		  

    General protein information

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    Preferred Names
    NAC domain containing protein 53
    NP_566376.1
    • NAC domain containing protein 53 (NAC053); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: multicellular organismal development, regulation of transcription; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: No apical meristem (NAM) protein (InterPro:IPR003441); BEST Arabidopsis thaliana protein match is: NAC domain containing protein 2 (TAIR:AT5G04410.1); Has 3039 Blast hits to 3027 proteins in 85 species: Archae - 0; Bacteria - 10; Metazoa - 0; Fungi - 7; Plants - 3017; Viruses - 0; Other Eukaryotes - 5 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      3271217..3274176
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001337881.1 → NP_001326104.1  NAC domain containing protein 53 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LN95

    2. NM_111885.4 → NP_566376.1  NAC domain containing protein 53 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566376.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LAH6, Q949N0, Q9SQY1
      UniProtKB/TrEMBL
      A0A178VIR2, A0A5S9XB33
      Conserved Domains (1) summary
      pfam02365
      Location:10 → 136
      NAM; No apical meristem (NAM) protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q949N0.1

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