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    CG43089 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 12798588, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG43089provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0262535
    Locus tag
    Dmel_CG43089
    See related
    AllianceGenome:FB:FBgn0262535
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG43089; lincRNA.427
    Summary
    Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG43089 in Genome Data Viewer
    Location:
    63E8-63E8; 3-8 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (3714027..3714717)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (3714027..3714717)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43485 Neighboring gene long non-coding RNA:CR45675 Neighboring gene uncharacterized protein Neighboring gene pickpocket 27 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comprehensive Identification and Alternative Splicing of Microexons in Drosophila. Pang TL, et al. Front Genet, 2021. PMID 33859668, Free PMC Article
    2. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article
    3. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article
    4. Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster. Liu X, et al. RNA, 2017 Dec. PMID 28851752, Free PMC Article
    5. The Release 6 reference sequence of the Drosophila melanogaster genome. Hoskins RA, et al. Genome Res, 2015 Mar. PMID 25589440, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables cullin family protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG43089-PB
    CG43089-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      3714027..3714717
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001300001.1 → NP_001286930.1  uncharacterized protein Dmel_CG43089, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286930.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F3YDE8, M9ND39
      Conserved Domains (2) summary
      pfam01466
      Location:95 → 139
      Skp1; Skp1 family, dimerization domain
      cl02518
      Location:9 → 111
      BTB; BTB/POZ domain

    2. NM_001259677.1 → NP_001246606.1  uncharacterized protein Dmel_CG43089, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246606.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F3YDE8, M9ND39
      Conserved Domains (2) summary
      pfam01466
      Location:95 → 139
      Skp1; Skp1 family, dimerization domain
      cl02518
      Location:9 → 111
      BTB; BTB/POZ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9ND39 M9ND39

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