U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG8745 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39530, updated on 17-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG8745provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036381
    Locus tag
    Dmel_CG8745
    See related
    AllianceGenome:FB:FBgn0036381
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8745
    Summary
    Predicted to enable ethanolamine-phosphate phospho-lyase activity. Involved in response to nicotine. Is expressed in several structures, including adult head; amnioserosa; amnioserosa primordium; mesoderm; and visceral mesoderm derivative. Orthologous to several human genes including ETNPPL (ethanolamine-phosphate phospho-lyase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG8745 in Genome Data Viewer
    Location:
    70C5-70C5; 3-41 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (13860027..13866905, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (13853127..13860005, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Tetraspanin 68C Neighboring gene Hemolectin Neighboring gene dyschronic Neighboring gene uncharacterized protein Neighboring gene Ral guanine nucleotide dissociation stimulator-like

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Quantitative trait transcripts for nicotine resistance in Drosophila melanogaster. Passador-Gurgel G, et al. Nat Genet, 2007 Feb. PMID 17237783
    2. Glial TGFβ activity promotes neuron survival in peripheral nerves. Lassetter AP, et al. J Cell Biol, 2023 Jan 2. PMID 36399182, Free PMC Article
    3. Elevation of glutamine level by selenophosphate synthetase 1 knockdown induces megamitochondrial formation in Drosophila cells. Shim MS, et al. J Biol Chem, 2009 Nov 20. PMID 19755423, Free PMC Article
    4. A Quantitative Genomic Approach for Analysis of Fitness and Stress Related Traits in a Drosophila melanogaster Model Population. Duun Rohde P, et al. Int J Genomics, 2016. PMID 27274984, Free PMC Article
    5. CLOCKWORK ORANGE promotes CLOCK-CYCLE activation via the putative Drosophila ortholog of CLOCK INTERACTING PROTEIN CIRCADIAN. Rivas GBS, et al. Curr Biol, 2021 Oct 11. PMID 34331859, Free PMC Article

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ethanolamine-phosphate phospho-lyase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transaminase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in response to nicotine IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG8745-PA
    NP_648665.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      13860027..13866905 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140408.3 → NP_648665.1  uncharacterized protein Dmel_CG8745 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648665.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95RV4, Q9VU95
      Related
      FBpp0075543
      Conserved Domains (2) summary
      cd00610
      Location:37 → 447
      OAT_like; Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase, ...
      COG0160
      Location:20 → 450
      GabT; 4-aminobutyrate aminotransferase or related aminotransferase [Amino acid transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VU95.2 Q9VU95

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous