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    ACS8 1-amino-cyclopropane-1-carboxylate synthase 8 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 829933, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ACS8
    Official Full Name
    1-amino-cyclopropane-1-carboxylate synthase 8
    Primary source
    TAIR:AT4G37770
    Locus tag
    AT4G37770
    See related
    Araport:AT4G37770
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    1-amino-cyclopropane-1-carboxylate synthase 8; T28I19.50; T28I19_50
    Summary
    Encodes an auxin inducible ACC synthase.
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    Genomic context

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    See ACS8 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    4
    Sequence:
    Chromosome: 4; NC_003075.7 (17752079..17754157)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene Integrase-type DNA-binding superfamily protein Neighboring gene squalene epoxidase 3 Neighboring gene myb domain protein 87 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis thalianaACS8 plays a crucial role in the early biosynthesis of ethylene elicited by Cu(2+) ions. Zhang B, et al. J Cell Sci, 2018 Jan 29. PMID 28775152
    2. Ethylene and auxin control the Arabidopsis response to decreased light intensity. Vandenbussche F, et al. Plant Physiol, 2003 Oct. PMID 12972669, Free PMC Article
    3. ACS4, a primary indoleacetic acid-responsive gene encoding 1-aminocyclopropane-1-carboxylate synthase in Arabidopsis thaliana. Structural characterization, expression in Escherichia coli, and expression characteristics in response to auxin [corrected]. Abel S, et al. J Biol Chem, 1995 Aug 11. PMID 7642574
    4. Abscisic Acid Antagonizes Ethylene Production through the ABI4-Mediated Transcriptional Repression of ACS4 and ACS8 in Arabidopsis. Dong Z, et al. Mol Plant, 2016 Jan 4. PMID 26410794
    5. The Arabidopsis 14-3-3 protein RARE COLD INDUCIBLE 1A links low-temperature response and ethylene biosynthesis to regulate freezing tolerance and cold acclimation. Catalá R, et al. Plant Cell, 2014 Aug. PMID 25122152, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis thaliana (At)ACS8 was identified as essential for the defense response and early ethylene biosynthesis induced by copper.
      Title: Arabidopsis thalianaACS8 plays a crucial role in the early biosynthesis of ethylene elicited by Cu(2+) ions.
    2. results demonstrate that ABA negatively regulates ethylene production through ABI4-mediated transcriptional repression of the ethylene biosynthesis genes ACS4 and ACS8
      Title: Abscisic Acid Antagonizes Ethylene Production through the ABI4-Mediated Transcriptional Repression of ACS4 and ACS8 in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_119939.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables 1-aminocyclopropane-1-carboxylate synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 1-aminocyclopropane-1-carboxylate synthase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables pyridoxal phosphate binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within 1-aminocyclopropane-1-carboxylate biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in ethylene biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ethylene biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    1-amino-cyclopropane-1-carboxylate synthase 8
    NP_195491.1
    • 1-amino-cyclopropane-1-carboxylate synthase 8 (ACS8); CONTAINS InterPro DOMAIN/s: 1-aminocyclopropane-1-carboxylate synthase (InterPro:IPR001176), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferase, class I/classII (InterPro:IPR004839), Aminotransferases, class-I, pyridoxal-phosphate-binding site (InterPro:IPR004838), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: 1-aminocyclopropane-1-carboxylate synthase 4 (TAIR:AT2G22810.1); Has 32273 Blast hits to 32271 proteins in 2940 species: Archae - 857; Bacteria - 22542; Metazoa - 664; Fungi - 765; Plants - 1331; Viruses - 0; Other Eukaryotes - 6114 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      17752079..17754157
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_119939.3 → NP_195491.1  1-amino-cyclopropane-1-carboxylate synthase 8 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195491.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9T065
      UniProtKB/TrEMBL
      A0A5S9XZI8, Q56Y32
      Conserved Domains (3) summary
      cd00609
      Location:77 → 426
      AAT_like; Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine ...
      PLN02450
      Location:1 → 468
      PLN02450; 1-aminocyclopropane-1-carboxylate synthase
      cl18945
      Location:3 → 147
      AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9T065.1

    Gene LinkOut

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