PYL10 PYR1-like 10 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: PYL10
Official Full Name: PYR1-like 10
Primary source: TAIR:AT4G27920
Locus tag: AT4G27920
See related: Araport:AT4G27920
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: PYR1-like 10; RCAR4; regulatory components of ABA receptor 4; T13J8.30; T13J8_30
Summary: Encodes a member of the PYR (pyrabactin resistance)/PYL(PYR1-like)/RCAR (regulatory components of ABA receptor) family proteins with 14 members. PYR/PYL/RCAR family proteins function as abscisic acid sensors. Mediate ABA-dependent regulation of protein phosphatase 2Cs ABI1 and ABI2.
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Genomic context

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See PYL10 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 3

Sequence:: Chromosome: 4; NC_003075.7 (13901142..13902000)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Using molecular dynamics simulations, the complete abscisic acid recognition pathways by two subtype receptors, PYL5 and PYL10, and a modified PYL5 receptor through tyrosine nitration, have been established.
Title: Dewetting Controls Plant Hormone Perception and Initiation of Drought Resistance Signaling.
Molecular dynamics simulations have been applied to two different PYL10-HAB1 complex heterodimer systems representing normal and magnesium deficient conditions. The heterodimer conformation and stability were delineated at high temperatures mimicking heat stress. Results showed that the thermostability of the heat stress response heterodimer was significantly dependent on the magnesium.
Title: Thermostability of the PYL-PP2C Heterodimer Is Dependent on Magnesium: In Silico Insights into the Link between Heat Stress Response and Magnesium Deficiency in Plants.
the crystal structures of PYL10 were determined in the apo- and ABA-bound states, with respective resolutions of 3.0 and 2.7A.
Title: Crystal structures of the Arabidopsis thaliana abscisic acid receptor PYL10 and its complex with abscisic acid.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_118930.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables abscisic acid binding	ISS Inferred from Sequence or Structural Similarity more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables protein homodimerization activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein phosphatase inhibitor activity	IDA Inferred from Direct Assay more info	PubMed
enables signaling receptor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in abscisic acid-activated signaling pathway	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISS Inferred from Sequence or Structural Similarity more info
located_in nucleus	ISM Inferred from Sequence Model more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: PYR1-like 10

NP_194521.2

PYR1-like 10 (PYL10); CONTAINS InterPro DOMAIN/s: Polyketide cyclase/dehydrase (InterPro:IPR019587); BEST Arabidopsis thaliana protein match is: regulatory components of ABA receptor 3 (TAIR:AT5G53160.2); Has 399 Blast hits to 399 proteins in 29 species: Archae - 0; Bacteria - 4; Metazoa - 0; Fungi - 0; Plants - 394; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

13901142..13902000

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_118930.3 → NP_194521.2 PYR1-like 10 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_194521.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q8H1R0, Q9SUE6

UniProtKB/TrEMBL

A0A178V0C5, A0A5S9XWI3

Conserved Domains (1) summary

cd07821
Location:27 → 172

PYR_PYL_RCAR_like; Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins