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    RAB1A RAB GTPase homolog 1A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834766, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RAB1A
    Official Full Name
    RAB GTPase homolog 1A
    Primary source
    TAIR:AT5G47200
    Locus tag
    AT5G47200
    See related
    Araport:AT5G47200
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS RAB GTPASE HOMOLOG D2B; ATRAB1A; ATRABD2B; MQL5.5; MQL5_5; RAB GTPase homolog 1A
    Summary
    AtRabD2b encodes a Rab GTPase, which plays important roles in pollen development, germination and tube elongation.
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    Genomic context

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    See RAB1A in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Sequence:
    Chromosome: 5; NC_003076.8 (19166859..19169093)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Plant VAMP (vesicle-associated membrane protein) family protein Neighboring gene Ribosomal protein L19 family protein Neighboring gene Hyaluronan / mRNA binding family Neighboring gene ethylene responsive element binding factor 2 Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AtRabD2b and AtRabD2c have overlapping functions in pollen development and pollen tube growth. Peng J, et al. BMC Plant Biol, 2011 Jan 26. PMID 21269510, Free PMC Article
    2. Genetic evidence that the higher plant Rab-D1 and Rab-D2 GTPases exhibit distinct but overlapping interactions in the early secretory pathway. Pinheiro H, et al. J Cell Sci, 2009 Oct 15. PMID 19789181, Free PMC Article
    3. CHARACTERIZATION OF A RABE (RAS GENE FROM RAT BRAIN E) GTPASE EXPRESSED DURING MORPHOGENESIS IN THE UNICELLULAR GREEN ALGA MICRASTERIAS DENTICULATA (ZYGNEMATOPHYCEAE, STREPTOPHYTA)(1). Vannerum K, et al. J Phycol, 2012 Jun. PMID 27011085
    4. Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2004 Jul. PMID 15060130
    5. Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. Ito J, et al. J Proteome Res, 2011 Apr 1. PMID 21166475

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Findings support a partially redundant role for AtRabD2b and AtRabD2c in vesicle trafficking during pollen tube growth that cannot be fulfilled by the remaining AtRabD family members.[AtRabD2b]
      Title: AtRabD2b and AtRabD2c have overlapping functions in pollen development and pollen tube growth.
    2. The Rab-D1 and Rab-D2 subclasses have overlapping functions in the early secretory pathway. [Rab-D2b]
      Title: Genetic evidence that the higher plant Rab-D1 and Rab-D2 GTPases exhibit distinct but overlapping interactions in the early secretory pathway.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_124091.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen tube growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plastid HDA PubMed 

    General protein information

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    Preferred Names
    RAB GTPase homolog 1A
    NP_568678.1
    • RAB GTPase homolog 1A (RAB1A); FUNCTIONS IN: GTP binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog 1C (TAIR:AT4G17530.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      19166859..19169093
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124091.5 → NP_568678.1  RAB GTPase homolog 1A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568678.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FPJ4, Q9LVT9
      UniProtKB/TrEMBL
      A0A178UEE0, A0A5S9YBS8, A0A7G2F3C7
      Conserved Domains (1) summary
      cd01869
      Location:7 → 172
      Rab1_Ypt1; Rab GTPase family 1 includes the yeast homolog Ypt1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FPJ4.1

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