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    SSP4b SCP1-like small phosphatase 4b [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827539, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SSP4b
    Official Full Name
    SCP1-like small phosphatase 4b
    Primary source
    TAIR:AT4G18140
    Locus tag
    AT4G18140
    See related
    Araport:AT4G18140
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F15J5.110; F15J5_110; SCP1-like small phosphatase 4b
    Summary
    Encodes a SCP1-like small phosphatase (SSP). Three SSPs form a unique group with long N-terminal extensions: AT5G46410 (SSP4), AT5G11860 (SSP5), AT4G18140 (SSP4b). SSP4 and SSP4b were localized exclusively in the nuclei, whereas SSP5 accumulated in both nuclei and cytoplasm. All three SSPs encodes active CTD phosphatases like animal SCP1 family proteins, with distinct substrate specificities: SSP4 and SSP4b could dephosphorylate both Ser2-PO(4) and Ser5-PO(4) of CTD, whereas SSP5 dephosphorylated only Ser5-PO(4).
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    Genomic context

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    See SSP4b in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    6
    Sequence:
    Chromosome: 4; NC_003075.7 (10046287..10049438, complement)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene miscRNA Neighboring gene phytochrome E Neighboring gene Serine/Threonine-kinase, putative (DUF1296) Neighboring gene Ca2+ activated outward rectifying K+ channel 6

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis SCP1-like small phosphatases differentially dephosphorylate RNA polymerase II C-terminal domain. Feng Y, et al. Biochem Biophys Res Commun, 2010 Jun 25. PMID 20513350
    2. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_001036584.3
    NM_001203831.1
    NM_117924.7

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA polymerase II CTD heptapeptide repeat phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein dephosphorylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SCP1-like small phosphatase 4b
    NP_001031661.2
    • SCP1-like small phosphatase 4b (SSP4b); CONTAINS InterPro DOMAIN/s: Dullard-like phosphatase domain (InterPro:IPR011948), NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: SCP1-like small phosphatase 4 (TAIR:AT5G46410.1); Has 2634 Blast hits to 2623 proteins in 242 species: Archae - 0; Bacteria - 12; Metazoa - 837; Fungi - 517; Plants - 509; Viruses - 1; Other Eukaryotes - 758 (source: NCBI BLink).
    NP_001190760.1
    • SCP1-like small phosphatase 4b (SSP4b); CONTAINS InterPro DOMAIN/s: Dullard-like phosphatase domain (InterPro:IPR011948), NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: SCP1-like small phosphatase 4 (TAIR:AT5G46410.1).
    NP_193548.7
    • SCP1-like small phosphatase 4b (SSP4b); CONTAINS InterPro DOMAIN/s: Dullard-like phosphatase domain (InterPro:IPR011948), NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: SCP1-like small phosphatase 4 (TAIR:AT5G46410.1); Has 2632 Blast hits to 2621 proteins in 242 species: Archae - 0; Bacteria - 12; Metazoa - 837; Fungi - 515; Plants - 509; Viruses - 1; Other Eukaryotes - 758 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      10046287..10049438 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001341262.1 → NP_001328766.1  SCP1-like small phosphatase 4b [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UYB5, A0A1P8B5P3, A0A654FQF2
      Conserved Domains (1) summary
      TIGR02251
      Location:269 → 423
      HIF-SF_euk; Dullard-like phosphatase domain

    2. NM_001341261.1 → NP_001328767.1  SCP1-like small phosphatase 4b [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UYB5, A0A1P8B5P3, A0A654FQF2
      Conserved Domains (1) summary
      TIGR02251
      Location:269 → 423
      HIF-SF_euk; Dullard-like phosphatase domain

    3. NM_001341263.1 → NP_001328768.1  SCP1-like small phosphatase 4b [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UYB5, A0A1P8B5P3, A0A654FQF2
      Conserved Domains (1) summary
      TIGR02251
      Location:269 → 423
      HIF-SF_euk; Dullard-like phosphatase domain

    4. NM_001036584.3 → NP_001031661.2  SCP1-like small phosphatase 4b [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031661.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UYB5, F4JQR6
      Conserved Domains (1) summary
      TIGR02251
      Location:269 → 423
      HIF-SF_euk; Dullard-like phosphatase domain

    5. NM_117924.7 → NP_193548.7  SCP1-like small phosphatase 4b [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_193548.7

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UYB5, F4JQR6
      Conserved Domains (1) summary
      TIGR02251
      Location:269 → 423
      HIF-SF_euk; Dullard-like phosphatase domain

    6. NM_001203831.1 → NP_001190760.1  SCP1-like small phosphatase 4b [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001190760.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UYB5, F4JQR8
      Conserved Domains (1) summary
      TIGR02251
      Location:269 → 423
      HIF-SF_euk; Dullard-like phosphatase domain
    Nucleotide Protein
    Heading Accession and Version

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