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    VPS26A vacuolar protein sorting 26A [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835435, updated on 18-Sep-2024

    Summary

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    Official Symbol
    VPS26A
    Official Full Name
    vacuolar protein sorting 26A
    Primary source
    TAIR:AT5G53530
    Locus tag
    AT5G53530
    See related
    Araport:AT5G53530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    MNC6.7; MNC6_7; vacuolar protein sorting 26A
    Summary
    Homolog of yeast retromer subunit VPS26. Part of a retromer-like protein complex involved in endosome to lysosome protein transport.
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    Genomic context

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    See VPS26A in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    12
    Sequence:
    Chromosome: 5; NC_003076.8 (21745937..21748719, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Transducin/WD40 repeat-like superfamily protein Neighboring gene oligopeptide transporter 9 Neighboring gene oligopeptide transporter 8 Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene YELLOW STRIPE like 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Retromer contributes to immunity-associated cell death in Arabidopsis. Munch D, et al. Plant Cell, 2015 Feb. PMID 25681156, Free PMC Article
    2. Plant retromer, localized to the prevacuolar compartment and microvesicles in Arabidopsis, may interact with vacuolar sorting receptors. Oliviusson P, et al. Plant Cell, 2006 May. PMID 16582012, Free PMC Article
    3. A Pan-plant Protein Complex Map Reveals Deep Conservation and Novel Assemblies. McWhite CD, et al. Cell, 2020 Apr 16. PMID 32191846, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_124733.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within endosome to lysosome transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in intracellular membrane-bounded organelle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in multivesicular body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of retromer complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of retromer complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vacuolar protein sorting 26A
    NP_200165.1
    • vacuolar protein sorting 26A (VPS26A); CONTAINS InterPro DOMAIN/s: Vacuolar protein sorting-associated protein 26 (InterPro:IPR005377); BEST Arabidopsis thaliana protein match is: vacuolar protein sorting 26B (TAIR:AT4G27690.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      21745937..21748719 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_124733.4 → NP_200165.1  vacuolar protein sorting 26A [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200165.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9FJD0
      UniProtKB/TrEMBL
      A0A178UT36, A0A5S9YET9
      Conserved Domains (1) summary
      pfam03643
      Location:8 → 283
      Vps26; Vacuolar protein sorting-associated protein 26
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FJD0.1

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