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    formin-like protein (DUF1421) [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828945, updated on 18-Sep-2024

    Summary

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    Official Full Name
    formin-like protein (DUF1421)
    Primary source
    TAIR:AT4G28300
    Locus tag
    AT4G28300
    See related
    Araport:AT4G28300
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F26K10.180; F26K10_180
    Summary
    Encodes a protein with 13.6% proline amino acids that is predicted to localize to the cell wall.
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (14014646..14017097)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene RING membrane-anchor 2 Neighboring gene uncharacterized protein Neighboring gene LORELEI-LIKE-GPI ANCHORED PROTEIN 3 Neighboring gene microtubule-associated protein Neighboring gene Glycosyl hydrolase superfamily protein Neighboring gene pyrroline-5-carboxylate reductase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation. Dorone Y, et al. Cell, 2021 Aug 5. PMID 34233164, Free PMC Article
    2. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation.
      Title: A prion-like protein regulator of seed germination undergoes hydration-dependent phase separation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_118970.6
    NM_202901.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of seed germination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to osmotic stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to water IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endosperm protein body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    formin-like protein (DUF1421)
    NP_194559.2
    • Protein of unknown function (DUF1421); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1421 (InterPro:IPR010820); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1421) (TAIR:AT5G14540.1); Has 69579 Blast hits to 42038 proteins in 1735 species: Archae - 58; Bacteria - 7637; Metazoa - 28439; Fungi - 15188; Plants - 8838; Viruses - 1343; Other Eukaryotes - 8076 (source: NCBI BLink).
    NP_974630.1
    • Protein of unknown function (DUF1421); CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF1421 (InterPro:IPR010820); BEST Arabidopsis thaliana protein match is: Protein of unknown function (DUF1421) (TAIR:AT5G14540.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      14014646..14017097
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_118970.6 → NP_194559.2  formin-like protein (DUF1421) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_194559.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8VZR8, Q9M0H8
      Conserved Domains (2) summary
      COG2882
      Location:92 → 173
      FliJ; Flagellar biosynthesis chaperone FliJ [Cell motility]
      pfam07223
      Location:146 → 479
      DUF1421; Protein of unknown function (DUF1421)

    2. NM_202901.2 → NP_974630.1  formin-like protein (DUF1421) [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974630.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UU73, F4JL78
      Conserved Domains (2) summary
      pfam07223
      Location:88 → 421
      DUF1421; Protein of unknown function (DUF1421)
      pfam15619
      Location:20 → 115
      Lebercilin; Ciliary protein causing Leber congenital amaurosis disease
    Nucleotide Protein
    Heading Accession and Version

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