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    NRPE3B DNA-directed RNA polymerase family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816032, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NRPE3B
    Official Full Name
    DNA-directed RNA polymerase family protein
    Primary source
    TAIR:AT2G15400
    Locus tag
    AT2G15400
    See related
    Araport:AT2G15400
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F26H6.8; F26H6_8; RBP36B
    Summary
    Non-catalytic subunit of Nuclear DNA-dependent RNA polymerase V; homologous to budding yeast RPB3 and the E. coli RNA polymerase alpha subunit. A closely related paralog, At2g15430 can substitute for At2g15400 in the context of Pol V and encodes the equivalent subunit of Pol II and Pol IV.
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    Genomic context

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    See NRPE3B in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (6712895..6714609)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene fucosyltransferase 4 Neighboring gene pseudo Neighboring gene myosin heavy chain-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis GLUTAMINE-RICH PROTEIN23 is essential for early embryogenesis and encodes a novel nuclear PPR motif protein that interacts with RNA polymerase II subunit III. Ding YH, et al. Plant Cell, 2006 Apr. PMID 16489121, Free PMC Article
    2. Association between 36- and 13.6-kDa alpha-like subunits of Arabidopsis thaliana RNA polymerase II. Ulmasov T, et al. J Biol Chem, 1996 Mar 1. PMID 8617787
    3. DTF1 is a core component of RNA-directed DNA methylation and may assist in the recruitment of Pol IV. Zhang H, et al. Proc Natl Acad Sci U S A, 2013 May 14. PMID 23637343, Free PMC Article
    4. A protein complex required for polymerase V transcripts and RNA- directed DNA methylation in Arabidopsis. Law JA, et al. Curr Biol, 2010 May 25. PMID 20409711, Free PMC Article
    5. Domains rearranged methyltransferase3 controls DNA methylation and regulates RNA polymerase V transcript abundance in Arabidopsis. Zhong X, et al. Proc Natl Acad Sci U S A, 2015 Jan 20. PMID 25561521, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001084425.2
    NM_127100.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-directed 5'-3' RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA polymerase IV complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of RNA polymerase V complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    DNA-directed RNA polymerase family protein
    NP_001077894.1
    • NRPE3B; FUNCTIONS IN: DNA-directed RNA polymerase activity, protein dimerization activity, DNA binding; INVOLVED IN: transcription; LOCATED IN: DNA-directed RNA polymerase V complex, DNA-directed RNA polymerase II, core complex; CONTAINS InterPro DOMAIN/s: DNA-directed RNA polymerase, insert domain (InterPro:IPR011262), DNA-directed RNA polymerase, dimerisation (InterPro:IPR011261), DNA-directed RNA polymerase, RpoA/D/Rpb3-type (InterPro:IPR011263), DNA-directed RNA polymerase, 30-40kDa subunit, conserved site (InterPro:IPR001514), DNA-directed RNA polymerase, RBP11-like (InterPro:IPR009025); BEST Arabidopsis thaliana protein match is: DNA-directed RNA polymerase family protein (TAIR:AT2G15430.1); Has 1353 Blast hits to 1352 proteins in 354 species: Archae - 242; Bacteria - 1; Metazoa - 277; Fungi - 354; Plants - 107; Viruses - 0; Other Eukaryotes - 372 (source: NCBI BLink).
    NP_179142.1
    • NRPE3B; FUNCTIONS IN: DNA-directed RNA polymerase activity, protein dimerization activity, DNA binding; INVOLVED IN: transcription; LOCATED IN: DNA-directed RNA polymerase V complex, DNA-directed RNA polymerase II, core complex; CONTAINS InterPro DOMAIN/s: DNA-directed RNA polymerase, insert domain (InterPro:IPR011262), DNA-directed RNA polymerase, dimerisation (InterPro:IPR011261), DNA-directed RNA polymerase, RpoA/D/Rpb3-type (InterPro:IPR011263), DNA-directed RNA polymerase, 30-40kDa subunit, conserved site (InterPro:IPR001514), DNA-directed RNA polymerase, RBP11-like (InterPro:IPR009025); BEST Arabidopsis thaliana protein match is: DNA-directed RNA polymerase family protein (TAIR:AT2G15430.1); Has 1357 Blast hits to 1356 proteins in 354 species: Archae - 243; Bacteria - 1; Metazoa - 278; Fungi - 347; Plants - 109; Viruses - 0; Other Eukaryotes - 379 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      6712895..6714609
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127100.4 → NP_179142.1  DNA-directed RNA polymerase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179142.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39212, Q9SJP1
      UniProtKB/TrEMBL
      A0A178VTE8, A0A384LLK9, A0A5S9WY89, A0A654EUN6, Q0WRA4
      Conserved Domains (1) summary
      cd07031
      Location:10 → 302
      RNAP_II_RPB3; RPB3 subunit of Eukaryotic RNA polymerase II

    2. NM_001084425.2 → NP_001077894.1  DNA-directed RNA polymerase family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077894.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A8MR04
      Conserved Domains (2) summary
      cd07031
      Location:10 → 209
      RNAP_II_RPB3; RPB3 subunit of Eukaryotic RNA polymerase II
      smart00662
      Location:22 → 226
      RPOLD; RNA polymerases D
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39212.2

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