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    SIS3 SUGAR-INSENSITIVE 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823954, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SIS3
    Official Full Name
    SUGAR-INSENSITIVE 3
    Primary source
    TAIR:AT3G47990
    Locus tag
    AT3G47990
    See related
    Araport:AT3G47990
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    SUGAR-INSENSITIVE 3
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    Genomic context

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    See SIS3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (17713094..17716349, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Integral membrane HPP family protein Neighboring gene aldehyde dehydrogenase 2B4 Neighboring gene cyclic nucleotide-gated channel 16

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SUGAR-INSENSITIVE3, a RING E3 ligase, is a new player in plant sugar response. Huang Y, et al. Plant Physiol, 2010 Apr. PMID 20147494, Free PMC Article
    2. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001339343.1
    NM_001339344.1
    NM_001339345.1
    NM_114668.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin-protein transferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables ubiquitin-protein transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sugar mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sugar mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SUGAR-INSENSITIVE 3
    NP_190382.2
    • SUGAR-INSENSITIVE 3 (SIS3); FUNCTIONS IN: ubiquitin-protein ligase activity, zinc ion binding; INVOLVED IN: sugar mediated signaling pathway; LOCATED IN: endomembrane system; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957); BEST Arabidopsis thaliana protein match is: RING/U-box superfamily protein (TAIR:AT5G66070.1); Has 9412 Blast hits to 9385 proteins in 270 species: Archae - 0; Bacteria - 0; Metazoa - 2601; Fungi - 698; Plants - 4895; Viruses - 18; Other Eukaryotes - 1200 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      17713094..17716349 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001339342.1 → NP_001325939.1  SUGAR-INSENSITIVE 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LMR7, A0A5S9XIX1

    2. NM_114668.3 → NP_190382.2  SUGAR-INSENSITIVE 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190382.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8GYT9, Q9SU62
      UniProtKB/TrEMBL
      A0A5S9XIX1, A0A654FFP7
      Conserved Domains (1) summary
      cd16474
      Location:234 → 278
      RING-H2_RNF111_like; RING finger, H2 subclass, found in RING finger proteins RNF111, RNF165, and similar proteins

    3. NM_001339344.1 → NP_001325940.1  SUGAR-INSENSITIVE 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VFR3, A0A1I9LMR5
      Conserved Domains (1) summary
      cd16474
      Location:177 → 221
      RING-H2_RNF111_like; RING finger, H2 subclass, found in RING finger proteins RNF111, RNF165, and similar proteins

    4. NM_001339343.1 → NP_001325938.1  SUGAR-INSENSITIVE 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VFR3, A0A1I9LMR5
      Conserved Domains (1) summary
      cd16474
      Location:177 → 221
      RING-H2_RNF111_like; RING finger, H2 subclass, found in RING finger proteins RNF111, RNF165, and similar proteins

    5. NM_001339345.1 → NP_001325937.1  SUGAR-INSENSITIVE 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VFR3, A0A1I9LMR5
      Conserved Domains (1) summary
      cd16474
      Location:177 → 221
      RING-H2_RNF111_like; RING finger, H2 subclass, found in RING finger proteins RNF111, RNF165, and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8GYT9.2

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