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    AGL66 AGAMOUS-like 66 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 844133, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AGL66
    Official Full Name
    AGAMOUS-like 66
    Primary source
    TAIR:AT1G77980
    Locus tag
    AT1G77980
    See related
    Araport:AT1G77980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AGAMOUS-like 66; F28K19.20; F28K19_20
    Summary
    Encodes a member of the MIKC (MADS box, Keratin binding domain, and C terminal domain containing)family of transcriptional regulators. AGL66 is expressed in pollen.It forms heterodimers with other MICK family members (AGL104). Involved in late stages of pollen development and pollen tube growth.
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    Genomic context

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    See AGL66 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    10
    Sequence:
    Chromosome: 1; NC_003070.9 (29314841..29317186, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Ribosomal protein L7Ae/L30e/S12e/Gadd45 family protein Neighboring gene AGAMOUS-like 67 Neighboring gene repressor ROX1-like protein Neighboring gene STAS domain / Sulfate transporter family Neighboring gene ncRNA Neighboring gene sulfate transporter 1;2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The ARID-HMG DNA-binding protein AtHMGB15 is required for pollen tube growth in Arabidopsis thaliana. Xia C, et al. Plant J, 2014 Sep. PMID 24923357
    2. MIKC* MADS domain heterodimers are required for pollen maturation and tube growth in Arabidopsis. Adamczyk BJ, et al. Plant Physiol, 2009 Apr. PMID 19211705, Free PMC Article
    3. MIKC* MADS-protein complexes bind motifs enriched in the proximal region of late pollen-specific Arabidopsis promoters. Verelst W, et al. Plant Physiol, 2007 Jan. PMID 17071640, Free PMC Article
    4. Wide-scale screening of T-DNA lines for transcription factor genes affecting male gametophyte development in Arabidopsis. Reňák D, et al. Sex Plant Reprod, 2012 Mar. PMID 22101548
    5. Comprehensive interaction map of the Arabidopsis MADS Box transcription factors. de Folter S, et al. Plant Cell, 2005 May. PMID 15805477, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_106447.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within pollen development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pollen maturation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in regulation of pollen tube growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    AGAMOUS-like 66
    NP_177921.2
    • AGAMOUS-like 66 (AGL66); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription, pollen development; LOCATED IN: nucleus; EXPRESSED IN: petal, leaf whorl, male gametophyte, flower, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Transcription factor, MADS-box (InterPro:IPR002100); BEST Arabidopsis thaliana protein match is: AGAMOUS-like 104 (TAIR:AT1G22130.1); Has 6165 Blast hits to 6165 proteins in 753 species: Archae - 0; Bacteria - 2; Metazoa - 622; Fungi - 302; Plants - 5159; Viruses - 0; Other Eukaryotes - 80 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      29314841..29317186 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_106447.4 → NP_177921.2  AGAMOUS-like 66 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_177921.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A0MEH0, Q1PFC2, Q76K85, Q7X9H4
      UniProtKB/TrEMBL
      A0A5S9WVC2, A0A654EQ65
      Conserved Domains (2) summary
      COG5068
      Location:1 → 263
      ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
      cd00265
      Location:2 → 75
      MADS_MEF2_like; MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1PFC2.1

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