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    FKBP13 FK506-binding protein 13 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834607, updated on 18-Sep-2024

    Summary

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    Official Symbol
    FKBP13
    Official Full Name
    FK506-binding protein 13
    Primary source
    TAIR:AT5G45680
    Locus tag
    AT5G45680
    See related
    Araport:AT5G45680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATFKBP13; FK506 BINDING PROTEIN 13; FK506-binding protein 13; MRA19.7; MRA19_7
    Summary
    Peptidyl-Prolyl Isomerase located in chloroplast thylakoid lumen
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    Genomic context

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    See FKBP13 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (18530834..18532337)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene adenine phosphoribosyltransferase Neighboring gene GDSL-like Lipase/Acylhydrolase superfamily protein Neighboring gene histone acetyltransferase (DUF1264) Neighboring gene Haloacid dehalogenase-like hydrolase (HAD) superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Immunophilin AtFKBP13 sustains all peptidyl-prolyl isomerase activity in the thylakoid lumen from Arabidopsis thaliana deficient in AtCYP20-2. Edvardsson A, et al. Biochemistry, 2007 Aug 21. PMID 17655280
    2. Peptidyl-prolyl isomerase activity in chloroplast thylakoid lumen is a dispensable function of immunophilins in Arabidopsis thaliana. Ingelsson B, et al. Plant Cell Physiol, 2009 Oct. PMID 19717822
    3. A chloroplast FKBP interacts with and affects the accumulation of Rieske subunit of cytochrome bf complex. Gupta R, et al. Proc Natl Acad Sci U S A, 2002 Nov 26. PMID 12424338, Free PMC Article
    4. Identification of potential targets for thylakoid oxidoreductase AtVKOR/LTO1 in chloroplasts. Lu Y, et al. Protein Pept Lett, 2014. PMID 25412899
    5. Thioredoxin targets of the plant chloroplast lumen and their implications for plastid function. Hall M, et al. Proteomics, 2010 Mar. PMID 20049866

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. AtFKBP13-lacking mutants showed a dramatic decrease in peptidyl-prolyl isomerase activity.
      Title: Peptidyl-prolyl isomerase activity in chloroplast thylakoid lumen is a dispensable function of immunophilins in Arabidopsis thaliana.
    2. None of the immunophilins in the chloroplast thylakoid lumen of Arabidopsis except AtCYP20-2 and AtFKBP13 appear to possess prolyl isomerase activity toward peptide substrates.
      Title: Immunophilin AtFKBP13 sustains all peptidyl-prolyl isomerase activity in the thylakoid lumen from Arabidopsis thaliana deficient in AtCYP20-2.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_123935.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables peptidyl-prolyl cis-trans isomerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast thylakoid lumen HDA PubMed 
    located_in plastid HDA PubMed 
    located_in thylakoid lumen HDA PubMed 

    General protein information

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    Preferred Names
    FK506-binding protein 13
    NP_199380.1
    • FK506-binding protein 13 (FKBP13); FUNCTIONS IN: FK506 binding, peptidyl-prolyl cis-trans isomerase activity; INVOLVED IN: protein folding; LOCATED IN: thylakoid lumen, chloroplast thylakoid lumen, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Peptidyl-prolyl cis-trans isomerase, FKBP-type (InterPro:IPR001179); BEST Arabidopsis thaliana protein match is: FK506-binding protein 16-2 (TAIR:AT4G39710.1); Has 10267 Blast hits to 9756 proteins in 1768 species: Archae - 130; Bacteria - 5575; Metazoa - 1746; Fungi - 494; Plants - 780; Viruses - 0; Other Eukaryotes - 1542 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      18530834..18532337
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_123935.5 → NP_199380.1  FK506-binding protein 13 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_199380.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8M8T4, Q9SCY2
      UniProtKB/TrEMBL
      A0A5S9YBB4, A0A7G2FDW7
      Conserved Domains (1) summary
      COG0545
      Location:88 → 206
      FkpA; FKBP-type peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SCY2.2

    Gene LinkOut

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