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    AGD4 ARF-GAP domain 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837629, updated on 18-Sep-2024

    Summary

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    Official Symbol
    AGD4
    Official Full Name
    ARF-GAP domain 4
    Primary source
    TAIR:AT1G10870
    Locus tag
    AT1G10870
    See related
    Araport:AT1G10870
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARF-GAP domain 4; T19D16.20; T19D16_20
    Summary
    A member of ARF GAP domain (AGD), A thaliana has 15 members, grouped into four classes. AGD4 belongs to the Class 1, together with AGD1, AGD2, and AGD3.
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    Genomic context

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    See AGD4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    19
    Sequence:
    Chromosome: 1; NC_003070.9 (3616610..3623806, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Leucine-rich repeat protein kinase family protein Neighboring gene cytochrome C oxidase assembly factor Neighboring gene ncRNA Neighboring gene core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein Neighboring gene core-2/I-branching beta-1,6-n-acetylglucosaminyltransferase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SCARFACE encodes an ARF-GAP that is required for normal auxin efflux and vein patterning in Arabidopsis. Sieburth LE, et al. Plant Cell, 2006 Jun. PMID 16698946, Free PMC Article
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001331933.1
    NM_100962.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    ARF-GAP domain 4
    NP_172556.2
    • ARF-GAP domain 4 (AGD4); FUNCTIONS IN: ARF GTPase activator activity, zinc ion binding; INVOLVED IN: regulation of ARF GTPase activity; LOCATED IN: cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Arf GTPase activating protein (InterPro:IPR001164), Pleckstrin homology-type (InterPro:IPR011993), Ankyrin repeat-containing domain (InterPro:IPR020683), BAR (InterPro:IPR004148), Pleckstrin homology (InterPro:IPR001849), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: ARF-GAP domain 2 (TAIR:AT1G60860.1); Has 23403 Blast hits to 15248 proteins in 655 species: Archae - 77; Bacteria - 1735; Metazoa - 12296; Fungi - 2244; Plants - 1395; Viruses - 252; Other Eukaryotes - 5404 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      3616610..3623806 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100962.4 → NP_172556.2  ARF-GAP domain 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172556.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04097, Q9SMX5
      UniProtKB/TrEMBL
      A0A178WDZ0, A0A5S9TSZ4
      Conserved Domains (5) summary
      cd07606
      Location:15 → 216
      BAR_SFC_plant; The Bin/Amphiphysin/Rvs (BAR) domain of the plant protein SCARFACE (SFC)
      smart00105
      Location:470 → 603
      ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
      cd13250
      Location:291 → 425
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:683 → 713
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:658 → 746
      Ank_2; Ankyrin repeats (3 copies)

    2. NM_001331933.1 → NP_001320312.1  ARF-GAP domain 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AMD8, A0A5S9TSZ4
      Conserved Domains (5) summary
      cd07606
      Location:15 → 216
      BAR_SFC_plant; The Bin/Amphiphysin/Rvs (BAR) domain of the plant protein SCARFACE (SFC)
      smart00105
      Location:470 → 608
      ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
      cd13250
      Location:291 → 425
      PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
      sd00045
      Location:688 → 718
      ANK; ANK repeat [structural motif]
      pfam12796
      Location:663 → 751
      Ank_2; Ankyrin repeats (3 copies)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SMX5.2

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