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    Nufip nufip [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40043, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Nufipprovided by FlyBase
    Official Full Name
    nufipprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036812
    Locus tag
    Dmel_CG4076
    See related
    AllianceGenome:FB:FBgn0036812
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG4076; Dmel\CG4076; NUFIP
    Summary
    Predicted to be involved in box C/D snoRNP assembly. Predicted to be active in nucleus. Orthologous to human NUFIP1 (nuclear FMR1 interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Nufip in Genome Data Viewer
    Location:
    75D8-75D8; 3-45 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (18746611..18748367, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (18739711..18741467, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43985 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45938 Neighboring gene Mediator complex subunit 11 Neighboring gene ftz transcription factor 1 Neighboring gene Autophagy-related 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Loss of Atg16 delays the alcohol-induced sedation response via regulation of Corazonin neuropeptide production in Drosophila. Varga K, et al. Sci Rep, 2016 Oct 6. PMID 27708416, Free PMC Article
    2. The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains. Maurer-Stroh S, et al. Trends Biochem Sci, 2003 Feb. PMID 12575993
    3. Drosophila melanogaster as a Model to Study the Multiple Phenotypes, Related to Genome Stability of the Fragile-X Syndrome. Specchia V, et al. Front Genet, 2019. PMID 30815010, Free PMC Article
    4. Highly rearranged chromosomes reveal uncoupling between genome topology and gene expression. Ghavi-Helm Y, et al. Nat Genet, 2019 Aug. PMID 31308546, Free PMC Article
    5. Drosophila Spag is the homolog of RNA polymerase II-associated protein 3 (RPAP3) and recruits the heat shock proteins 70 and 90 (Hsp70 and Hsp90) during the assembly of cellular machineries. Benbahouche Nel H, et al. J Biol Chem, 2014 Feb 28. PMID 24394412, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in box C/D snoRNP assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    nufip
    Names
    CG4076-PA
    Nufip-PA
    nuclear Fmr1 interacting protein
    nuclear Fragile-X mental retardation Protein-interacting protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      18746611..18748367 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140801.4 → NP_649058.1  nufip [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649058.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      N0D6Q9, Q9VVS5
      Related
      FBpp0074855
      Conserved Domains (1) summary
      pfam10453
      Location:126 → 180
      NUFIP1; Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95TV7 Q95TV7
    Q9VVS5 Q9VVS5

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