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    CG4239 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32606, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG4239provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030745
    Locus tag
    Dmel_CG4239
    See related
    AllianceGenome:FB:FBgn0030745
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG4239
    Summary
    Predicted to enable potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in sarcoplasmic reticulum. Is expressed in adult head; adult heart; indirect flight muscle cell; larval muscle system; and larval somatic muscle cell. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 14. Orthologous to human TMEM38A (transmembrane protein 38A) and TMEM38B (transmembrane protein 38B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG4239 in Genome Data Viewer
    Location:
    14C2-14C2; 1-53 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16385278..16388702)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (16279311..16282735)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene Furin 2 Neighboring gene uncharacterized protein Neighboring gene TH1 Neighboring gene meiotic 41 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables potassium channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in potassium ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in sarcoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG4239-PA
    CG4239-PB
    CG4239-PC
    CG4239-PD

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      16385278..16388702
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_167515.2NP_727972.1  uncharacterized protein Dmel_CG4239, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727972.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VXG9
      Related
      FBpp0074044
      Conserved Domains (1) summary
      pfam05197
      Location:42226
      TRIC; TRIC channel
    2. NM_132894.3NP_573122.1  uncharacterized protein Dmel_CG4239, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573122.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VXG9
      Related
      FBpp0074045
      Conserved Domains (1) summary
      pfam05197
      Location:42226
      TRIC; TRIC channel
    3. NM_167516.2NP_727973.1  uncharacterized protein Dmel_CG4239, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727973.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VXG9
      Related
      FBpp0074046
      Conserved Domains (1) summary
      pfam05197
      Location:42226
      TRIC; TRIC channel
    4. NM_001298396.1NP_001285325.1  uncharacterized protein Dmel_CG4239, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285325.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VXG9
      Conserved Domains (1) summary
      pfam05197
      Location:42226
      TRIC; TRIC channel