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    CG5913 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43132, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG5913provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039385
    Locus tag
    Dmel_CG5913
    See related
    AllianceGenome:FB:FBgn0039385
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG5913
    Summary
    Predicted to enable RNA binding activity. Predicted to be located in cytoplasm and nucleus. Predicted to be part of tRNA-splicing ligase complex. Is expressed in several structures, including adult head; embryonic/larval midgut; ganglia; and larval nervous system. Orthologous to several human genes including FAM98A (family with sequence similarity 98 member A) and FAM98B (family with sequence similarity 98 member B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG5913 in Genome Data Viewer
    Location:
    96F6-96F6; 3-89 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (25893495..25895026)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (21719217..21720748)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Signal peptide peptidase-like Neighboring gene Lnk Neighboring gene Sodesque Neighboring gene Multicopper oxidase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Rare variants in MYH15 modify amyotrophic lateral sclerosis risk. Kim H, et al. Hum Mol Genet, 2019 Jul 15. PMID 30985904, Free PMC Article
    2. Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. Slack C, et al. PLoS Genet, 2010 Mar 19. PMID 20333234, Free PMC Article
    3. The Septate Junction Protein Tsp2A Restricts Intestinal Stem Cell Activity via Endocytic Regulation of aPKC and Hippo Signaling. Xu C, et al. Cell Rep, 2019 Jan 15. PMID 30650359, Free PMC Article
    4. A comprehensive Drosophila resource to identify key functional interactions between SARS-CoV-2 factors and host proteins. Guichard A, et al. Cell Rep, 2023 Aug 29. PMID 37480566, Free PMC Article
    5. In vivo profiling of the Zucchini proximal proteome in the Drosophila ovary. Nguyen TTM, et al. Development, 2023 Feb 15. PMID 36762624

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    part_of tRNA-splicing ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG5913-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      25893495..25895026
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143182.4 → NP_651439.2  uncharacterized protein Dmel_CG5913 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651439.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q960C1, Q9VBK9
      Related
      FBpp0084312
      Conserved Domains (1) summary
      pfam10239
      Location:9 → 328
      DUF2465; Protein of unknown function (DUF2465)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q960C1 Q960C1
    Q9VBK9 Q9VBK9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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