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    CG2604 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40623, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG2604provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0037298
    Locus tag
    Dmel_CG2604
    See related
    AllianceGenome:FB:FBgn0037298
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CT40966; Dmel\CG2604; Sccpdh1
    Summary
    Predicted to be involved in glycolipid biosynthetic process. Predicted to be active in lipid droplet. Is expressed in adult head; adult heart; and organism. Orthologous to human SCCPDH (saccharopine dehydrogenase (putative)). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG2604 in Genome Data Viewer
    Location:
    82F6-82F6; 3-47.5 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (5221632..5223365, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (1047354..1049087, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Proteasome beta2 subunit-related 2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Vacuolar protein sorting 37B Neighboring gene Katanin 60

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The genetic basis of adaptation to copper pollution in Drosophila melanogaster. Everman ER, et al. Front Genet, 2023. PMID 37082199, Free PMC Article
    2. Transcriptional regulation by CHIP/LDB complexes. Bronstein R, et al. PLoS Genet, 2010 Aug 12. PMID 20730086, Free PMC Article
    3. Protein correlation profiles identify lipid droplet proteins with high confidence. Krahmer N, et al. Mol Cell Proteomics, 2013 May. PMID 23319140, Free PMC Article
    4. The lipid-droplet proteome reveals that droplets are a protein-storage depot. Cermelli S, et al. Curr Biol, 2006 Sep 19. PMID 16979555
    5. Genome-wide expression analysis in Drosophila reveals genes controlling circadian behavior. Ceriani MF, et al. J Neurosci, 2002 Nov 1. PMID 12417656, Free PMC Article

    See all (27) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in glycolipid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in lipid droplet IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG2604-PA
    CG2604-PB
    CG2604-PC
    saccheropin dehydrogenase
    saccheropin dehydrogenase 1
    NP_649517.1
    NP_730896.1
    NP_730897.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      5221632..5223365 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169030.3 → NP_730897.1  uncharacterized protein Dmel_CG2604, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730897.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VN86
      Related
      FBpp0078471
      Conserved Domains (2) summary
      COG3268
      Location:7 → 426
      COG3268; Uncharacterized conserved protein, related to short-chain dehydrogenases [Function unknown]
      pfam03435
      Location:8 → 139
      Sacchrp_dh_NADP; Saccharopine dehydrogenase NADP binding domain

    2. NM_169029.3 → NP_730896.1  uncharacterized protein Dmel_CG2604, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_730896.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VN86
      Related
      FBpp0078472
      Conserved Domains (2) summary
      COG3268
      Location:7 → 426
      COG3268; Uncharacterized conserved protein, related to short-chain dehydrogenases [Function unknown]
      pfam03435
      Location:8 → 139
      Sacchrp_dh_NADP; Saccharopine dehydrogenase NADP binding domain

    3. NM_141260.4 → NP_649517.1  uncharacterized protein Dmel_CG2604, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649517.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VN86
      Related
      FBpp0078470
      Conserved Domains (2) summary
      COG3268
      Location:7 → 426
      COG3268; Uncharacterized conserved protein, related to short-chain dehydrogenases [Function unknown]
      pfam03435
      Location:8 → 139
      Sacchrp_dh_NADP; Saccharopine dehydrogenase NADP binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VN86 Q9VN86

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