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    Nubp2 NUBP iron-sulfur cluster assembly factor 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40282, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nubp2provided by FlyBase
    Official Full Name
    NUBP iron-sulfur cluster assembly factor 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0037011
    Locus tag
    Dmel_CG4858
    See related
    AllianceGenome:FB:FBgn0037011
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Cfd1; CG4858; Dmel\CG4858
    Summary
    Predicted to enable iron-sulfur cluster binding activity. Predicted to contribute to ATP hydrolysis activity. Predicted to be involved in iron-sulfur cluster assembly. Predicted to be part of cytosolic [4Fe-4S] assembly scaffold complex. Predicted to be active in cytosol. Is expressed in organism. Orthologous to human NUBP2 (NUBP iron-sulfur cluster assembly factor 2, cytosolic). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Nubp2 in Genome Data Viewer
    Location:
    77C7-77C7; 3-47 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (20526576..20527910)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (20519676..20521010)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Phosphatidylserine synthase Neighboring gene Reduction in Cnn dots 2 Neighboring gene uncharacterized protein Neighboring gene long noncoding RNA: testis-specific 3

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables 4 iron, 4 sulfur cluster binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to ATP hydrolysis activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables ATP-dependent FeS chaperone activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables iron-sulfur cluster binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in iron-sulfur cluster assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in iron-sulfur cluster assembly IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic [4Fe-4S] assembly scaffold complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    NUBP iron-sulfur cluster assembly factor 2
    Names
    CG4858-PA
    Nubp2-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      20526576..20527910
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140986.3NP_649243.1  NUBP iron-sulfur cluster assembly factor 2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649243.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9VPD2
      Related
      FBpp0077868
      Conserved Domains (2) summary
      TIGR01969
      Location:8254
      minD_arch; cell division ATPase MinD, archaeal
      pfam10609
      Location:4254
      ParA; NUBPL iron-transfer P-loop NTPase