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    CG7460 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39973, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG7460provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0036749
    Locus tag
    Dmel_CG7460
    See related
    AllianceGenome:FB:FBgn0036749
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG7460
    Summary
    Predicted to enable polyamine oxidase activity. Predicted to be active in cytoplasm. Is expressed in adult head. Orthologous to human SMOX (spermine oxidase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG7460 in Genome Data Viewer
    Location:
    74F4-75A1; 3-45 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17740540..17742540)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17733640..17735640)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Ccn Neighboring gene Chemosensory protein B 74a Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Adenosine deaminase-related growth factor B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599810, Free PMC Article
    2. A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Neely GG, et al. Cell, 2010 Apr 2. PMID 20371351, Free PMC Article
    3. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    4. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848
    5. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polyamine oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG7460-PB
    CG7460-PC
    NP_001261998.1
    NP_649004.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17740540..17742540
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_140747.2 → NP_649004.1  uncharacterized protein Dmel_CG7460, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649004.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VVK1
      Related
      FBpp0074952
      Conserved Domains (2) summary
      pfam01593
      Location:32 → 476
      Amino_oxidase; Flavin containing amine oxidoreductase
      pfam13450
      Location:33 → 74
      NAD_binding_8; NAD(P)-binding Rossmann-like domain

    2. NM_001275069.1 → NP_001261998.1  uncharacterized protein Dmel_CG7460, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261998.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VVK1
      Conserved Domains (2) summary
      pfam01593
      Location:32 → 476
      Amino_oxidase; Flavin containing amine oxidoreductase
      pfam13450
      Location:33 → 74
      NAD_binding_8; NAD(P)-binding Rossmann-like domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VVK1 Q9VVK1

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