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    CG8641 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38771, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG8641provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035733
    Locus tag
    Dmel_CG8641
    See related
    AllianceGenome:FB:FBgn0035733
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8641; Q9VS10
    Summary
    Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in signal transduction. Orthologous to several human genes including RASD2 (RASD family member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8641 in Genome Data Viewer
    Location:
    65E2-65E3; 3-19 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7058930..7077462, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7052030..7070562, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Multiplexin Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR45832 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cuticular protein 65Ea Neighboring gene Cuticular protein 65Eb

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Evolutionary expansion of the Ras switch regulatory module in eukaryotes. Díez D, et al. Nucleic Acids Res, 2011 Jul. PMID 21447561, Free PMC Article
    2. Human RAS superfamily proteins and related GTPases. Colicelli J. Sci STKE, 2004 Sep 7. PMID 15367757, Free PMC Article
    3. Genome-wide view of cell fate specification: ladybird acts at multiple levels during diversification of muscle and heart precursors. Junion G, et al. Genes Dev, 2007 Dec 1. PMID 18056427, Free PMC Article
    4. Cellular diversity in the Drosophila midbrain revealed by single-cell transcriptomics. Croset V, et al. Elife, 2018 Apr 19. PMID 29671739, Free PMC Article
    5. The impact of genome variation and diet on the metabolic phenotype and microbiome composition of Drosophila melanogaster. Jehrke L, et al. Sci Rep, 2018 Apr 18. PMID 29670218, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables G-protein beta-subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8641-PA
    CG8641-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      7058930..7077462 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274565.1 → NP_001261494.1  uncharacterized protein Dmel_CG8641, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261494.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VS10
      Conserved Domains (2) summary
      cd04143
      Location:167 → 434
      Rhes_like; Ras homolog enriched in striatum (Rhes) and activator of G-protein signaling 1 (Dexras1/AGS1)
      smart00173
      Location:167 → 338
      RAS; Ras subfamily of RAS small GTPases

    2. NM_139816.2 → NP_648073.1  uncharacterized protein Dmel_CG8641, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648073.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VS10
      Related
      FBpp0076640
      Conserved Domains (2) summary
      cd04143
      Location:167 → 434
      Rhes_like; Ras homolog enriched in striatum (Rhes) and activator of G-protein signaling 1 (Dexras1/AGS1)
      smart00173
      Location:167 → 338
      RAS; Ras subfamily of RAS small GTPases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VS10 Q9VS10

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