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    CG34057 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3885645, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG34057provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0054057
    Locus tag
    Dmel_CG34057
    See related
    AllianceGenome:FB:FBgn0054057
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13904; dC1GalT6; Dmel\CG34057
    Summary
    Predicted to enable glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Tn polyagglutination syndrome and hemolytic-uremic syndrome. Orthologous to human C1GALT1C1 (C1GALT1 specific chaperone 1) and C1GALT1C1L (C1GALT1 specific chaperone 1 like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG34057 in Genome Data Viewer
    Location:
    61D4-61D4; 3-0.5 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (897380..898772)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (897380..898772)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Ubiquitin specific protease 10 Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46200 Neighboring gene materazzi

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of mucin-type core-1 beta1-3 galactosyltransferase homologous enzymes in Drosophila melanogaster. Müller R, et al. FEBS J, 2005 Sep. PMID 16128800
    2. Requirement for a core 1 galactosyltransferase in the Drosophila nervous system. Lin YR, et al. Dev Dyn, 2008 Dec. PMID 18985719, Free PMC Article
    3. Phenotype-based clustering of glycosylation-related genes by RNAi-mediated gene silencing. Yamamoto-Hino M, et al. Genes Cells, 2015 Jun. PMID 25940448, Free PMC Article
    4. High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Batut P, et al. Genome Res, 2013 Jan. PMID 22936248, Free PMC Article
    5. Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species. Sanfilippo P, et al. Genome Biol, 2017 Nov 30. PMID 29191225, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG34057-PA
    CG34057-PB
    NP_001033980.2
    NP_001033981.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      897380..898772
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001038891.2 → NP_001033980.2  uncharacterized protein Dmel_CG34057, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033980.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      C9QP10, Q2PE08
      Conserved Domains (1) summary
      cl21608
      Location:93 → 243
      Galactosyl_T; Galactosyltransferase

    2. NM_001038892.2 → NP_001033981.1  uncharacterized protein Dmel_CG34057, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033981.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C9QP10, Q2PE09
      Conserved Domains (1) summary
      cl21608
      Location:82 → 232
      Galactosyl_T; Galactosyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q2PE08 Q2PE08
    Q2PE09 Q2PE09

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