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    mms4 Methyl methanesulfonate sensitivity 4 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36136, updated on 9-Dec-2024

    Summary

    Official Symbol
    mms4provided by FlyBase
    Official Full Name
    Methyl methanesulfonate sensitivity 4provided by FlyBase
    Primary source
    FLYBASE:FBgn0033549
    Locus tag
    Dmel_CG12936
    See related
    AllianceGenome:FB:FBgn0033549
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12936; Dmel\CG12936; EME1
    Summary
    Predicted to enable DNA binding activity and nuclease activity. Predicted to be involved in DNA repair. Predicted to be located in nucleus. Predicted to be part of Holliday junction resolvase complex. Is expressed in organism. Orthologous to several human genes including EME1 (essential meiotic structure-specific endonuclease 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See mms4 in Genome Data Viewer
    Location:
    47C1-47C1; 2-63 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10811078..10812215)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6698583..6699720)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene windei Neighboring gene uncharacterized protein Neighboring gene Nop10 ribonucleoprotein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene diego

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of Holliday junction resolvase complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    methyl methanesulfonate sensitivity 4
    Names
    CG12936-PA
    methyl methanesulfonate sensitivity 4 ortholog
    mms4-PA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      10811078..10812215
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136767.3NP_610611.1  methyl methanesulfonate sensitivity 4 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610611.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1Z8C0, Q7JZM5
      Related
      FBpp0087317
      Conserved Domains (1) summary
      pfam02732
      Location:48179
      ERCC4; ERCC4 domain