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    slf schlaff [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 33678, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slfprovided by FlyBase
    Official Full Name
    schlaffprovided by FlyBase
    Primary source
    FLYBASE:FBgn0287234
    Locus tag
    Dmel_CG3244
    See related
    AllianceGenome:FB:FBgn0287234
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG3244; Clect27; Dmel\CG3244; l(2)25Aa; Slf
    Summary
    Predicted to enable carbohydrate binding activity. Is expressed in adult head; embryonic dorsal epidermis; embryonic head epidermis; and embryonic ventral epidermis. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See slf in Genome Data Viewer
    Location:
    25A6-25A6; 2-13 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (4796600..4801923, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (4796600..4801923, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene factor of interpulse interval Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR45297 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pluripotency and a secretion mechanism of Drosophila transglutaminase. Shibata T, et al. J Biochem, 2018 Mar 1. PMID 28992227
    2. Blastoderm-differential and blastoderm-specific genes of Drosophila melanogaster. Roark M, et al. Dev Biol, 1985 Jun. PMID 2581833
    3. The putative C-type lectin Schlaff ensures epidermal barrier compactness in Drosophila. Zuber R, et al. Sci Rep, 2019 Mar 29. PMID 30926832, Free PMC Article
    4. Protein crosslinking by transglutaminase controls cuticle morphogenesis in Drosophila. Shibata T, et al. PLoS One, 2010 Oct 18. PMID 20976106, Free PMC Article
    5. Form and function of the apical extracellular matrix: new insights from Caenorhabditis elegans, Drosophila melanogaster, and the vertebrate inner ear. Li Zheng S, et al. Fac Rev, 2020. PMID 33659959, Free PMC Article

    See all (50) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables carbohydrate binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    schlaff
    Names
    C-type lectin 27kD
    CG3244-PA
    CG3244-PB
    slf-PA
    slf-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      4796600..4801923 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_135014.3 → NP_608858.3  schlaff, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_608858.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZK9, Q9VR27
      Related
      FBpp0077108
      Conserved Domains (1) summary
      cd00037
      Location:67 → 213
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

    2. NM_001273117.1 → NP_001260046.1  schlaff, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260046.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZK9, Q9VR27
      Conserved Domains (1) summary
      cd00037
      Location:67 → 213
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SZK9 Q8SZK9

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