U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    CG16756 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31460, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    CG16756provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029765
    Locus tag
    Dmel_CG16756
    See related
    AllianceGenome:FB:FBgn0029765
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RH17440; Dmel\CG16756
    Summary
    Predicted to enable lysozyme activity. Predicted to be involved in defense response to Gram-negative bacterium. Predicted to be located in extracellular space. Is expressed in wing disc. Orthologous to several human genes including LYZL1 (lysozyme like 1); LYZL2 (lysozyme like 2); and LYZL6 (lysozyme like 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See CG16756 in Genome Data Viewer
    Location:
    4F10-4F10; 1-11 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5427517..5428217)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5321550..5322250)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene spoonbill Neighboring gene Ubiquitin specific protease 16/45 Neighboring gene long non-coding RNA:CR45517 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Drosophila spoonbill encodes a dual-specificity A-kinase anchor protein essential for oogenesis. Hadad M, et al. Mech Dev, 2011 Sep-Dec. PMID 21983075
    2. Characterization of the c-type lysozyme gene family in Anopheles gambiae. Li B, et al. Gene, 2005 Nov 7. PMID 16137842
    3. The Spalt Transcription Factors Generate the Transcriptional Landscape of the Drosophila melanogaster Wing Pouch Central Region. Organista MF, et al. PLoS Genet, 2015 Aug. PMID 26241320, Free PMC Article
    4. Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. Waterhouse RM, et al. Science, 2007 Jun 22. PMID 17588928, Free PMC Article
    5. Parasite-specific immune response in adult Drosophila melanogaster: a genomic study. Roxström-Lindquist K, et al. EMBO Rep, 2004 Feb. PMID 14749722, Free PMC Article

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables lysozyme activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lysozyme activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in defense response to Gram-negative bacterium ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular space ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    uncharacterized protein
    Names
    CG16756-PA
    NP_572222.2

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      5427517..5428217
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_131994.3 → NP_572222.2  uncharacterized protein Dmel_CG16756 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572222.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SZL1, Q9W4C2
      Related
      FBpp0070742
      Conserved Domains (1) summary
      cd00119
      Location:30 → 145
      LYZ1; C-type lysozyme (1, 4-beta-N-acetylmuramidase, LYZ) and alpha-lactalbumin (lactose synthase B protein, LA). They have a close evolutionary relationship and similar tertiary structure, however, functionally they are quite different. Lysozymes have ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W4C2 Q9W4C2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous