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    CG13375 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 30976, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13375provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040370
    Locus tag
    Dmel_CG13375
    See related
    AllianceGenome:FB:FBgn0040370
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13375; EG:BACR37P7.8
    Summary
    Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13375 in Genome Data Viewer
    Location:
    1A1-1A1; 1-0 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (283186..294962, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (177219..188995, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene erect wing Neighboring gene mir-980 stem loop Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Odorant receptor 1a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An expanded toolkit for gene tagging based on MiMIC and scarless CRISPR tagging in Drosophila. Li-Kroeger D, et al. Elife, 2018 Aug 9. PMID 30091705, Free PMC Article
    2. Evolutionary expansion of the Ras switch regulatory module in eukaryotes. Díez D, et al. Nucleic Acids Res, 2011 Jul. PMID 21447561, Free PMC Article
    3. DmGTSF1 is necessary for Piwi-piRISC-mediated transcriptional transposon silencing in the Drosophila ovary. Ohtani H, et al. Genes Dev, 2013 Aug 1. PMID 23913921, Free PMC Article
    4. Human RAS superfamily proteins and related GTPases. Colicelli J. Sci STKE, 2004 Sep 7. PMID 15367757, Free PMC Article
    5. Using single-cell RNA sequencing to generate predictive cell-type-specific split-GAL4 reagents throughout development. Chen YD, et al. Proc Natl Acad Sci U S A, 2023 Aug 8. PMID 37523539, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    mobile_element

    • Loc: c285253-285147 mobile_element_type = transposon:INE-1{}4708
    • Loc: c291089-290813 mobile_element_type = transposon:INE-1{}4711
    • Loc: c292994-292626 mobile_element_type = transposon:G3{}1

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables GDP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13375-PA
    CG13375-PB
    CG13375-PC

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      283186..294962 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001169157.2 → NP_001162628.1  uncharacterized protein Dmel_CG13375, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001162628.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NF75, Q9W5G7
      Conserved Domains (2) summary
      cd04147
      Location:49 → 239
      Ras_dva; Ras - dorsal-ventral anterior localization (Ras-dva) family
      smart00173
      Location:48 → 215
      RAS; Ras subfamily of RAS small GTPases

    2. NM_130481.4 → NP_569837.2  uncharacterized protein Dmel_CG13375, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_569837.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NF75, Q9W5G7
      Related
      FBpp0070098
      Conserved Domains (2) summary
      cd04147
      Location:49 → 239
      Ras_dva; Ras - dorsal-ventral anterior localization (Ras-dva) family
      smart00173
      Location:48 → 215
      RAS; Ras subfamily of RAS small GTPases

    3. NM_001297806.1 → NP_001284735.1  uncharacterized protein Dmel_CG13375, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001284735.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JC14
      Conserved Domains (2) summary
      cd04147
      Location:20 → 210
      Ras_dva; Ras - dorsal-ventral anterior localization (Ras-dva) family
      smart00173
      Location:19 → 186
      RAS; Ras subfamily of RAS small GTPases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9W5G7 Q9W5G7
    X2JC14 X2JC14

    Gene LinkOut

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