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    SmF Small ribonucleoprotein particle protein SmF [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36314, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SmFprovided by FlyBase
    Official Full Name
    Small ribonucleoprotein particle protein SmFprovided by FlyBase
    Primary source
    FLYBASE:FBgn0000426
    Locus tag
    Dmel_CG16792
    See related
    AllianceGenome:FB:FBgn0000426
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:GM23968; CG16792; Deb; deb-b; Deb-B; DebB; dF; Dmel\CG16792; F-Sm; snRNP-F
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of catalytic step 2 spliceosome and precatalytic spliceosome. Orthologous to human SNRPF (small nuclear ribonucleoprotein polypeptide F). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See SmF in Genome Data Viewer
    Location:
    48E6-48E7; 2-66 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12183844..12184310, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8071349..8071815, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR45264 Neighboring gene uncharacterized protein Neighboring gene washout Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 6g1 Neighboring gene Cytochrome P450 6g2 Neighboring gene Cytochrome P450 6t3 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence and expression of two regulated transcription units during Drosophila melanogaster development: Deb-A and Deb-B. Vincent WS 3rd, et al. Biochim Biophys Acta, 1990 May 24. PMID 1694092
    2. The trk family of tyrosine protein kinase receptors. Barbacid M, et al. Biochim Biophys Acta, 1991 Dec 10. PMID 1751544
    3. Precursor RNA processing 3 is required for male fertility, and germline stem cell self-renewal and differentiation via regulating spliceosome function in Drosophila testes. Chen X, et al. Sci Rep, 2019 Jul 10. PMID 31292463, Free PMC Article
    4. Dtrk, a Drosophila gene related to the trk family of neurotrophin receptors, encodes a novel class of neural cell adhesion molecule. Pulido D, et al. EMBO J, 1992 Feb. PMID 1371458, Free PMC Article
    5. Small ribonucleoprotein particle protein SmD3 governs the homeostasis of germline stem cells and the crosstalk between the spliceosome and ribosome signals in Drosophila. Yu J, et al. FASEB J, 2019 Jul. PMID 30921522

    See all (54) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mRNA splicing, via spliceosome IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in spliceosomal snRNP assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of U1 snRNP IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of catalytic step 2 spliceosome HDA PubMed 
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of pICln-Sm protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of precatalytic spliceosome HDA PubMed 
    part_of small nuclear ribonucleoprotein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    part_of small nuclear ribonucleoprotein complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of spliceosomal complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    small ribonucleoprotein particle protein SmF
    Names
    CG16792-PA
    SmF-PA
    developmental embryonic B

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      12183844..12184310 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078984.4 → NP_523708.2  small ribonucleoprotein particle protein SmF [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523708.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q24297, Q9V672
      Related
      FBpp0087118
      Conserved Domains (1) summary
      cd01722
      Location:8 → 76
      Sm_F; Sm protein F
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q24297.2 Q24297

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