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    CG13384 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 34160, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG13384provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0032036
    Locus tag
    Dmel_CG13384
    See related
    AllianceGenome:FB:FBgn0032036
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG13384
    Summary
    Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport. Predicted to be active in vacuolar membrane. Is expressed in adult abdomen; adult head; and adult thorax. Human ortholog(s) of this gene implicated in iminoglycinuria. Orthologous to several human genes including SLC36A1 (solute carrier family 36 member 1); SLC36A2 (solute carrier family 36 member 2); and SLC36A3 (solute carrier family 36 member 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG13384 in Genome Data Viewer
    Location:
    29B4-29C1; 2-31 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (8384455..8388804)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (8384455..8388804)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Reduction in Cnn dots 4 Neighboring gene Defender against apoptotic cell death 1 Neighboring gene uncharacterized protein Neighboring gene small nuclear RNA U6atac Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Adipocyte amino acid sensing controls adult germline stem cell number via the amino acid response pathway and independently of Target of Rapamycin signaling in Drosophila. Armstrong AR, et al. Development, 2014 Dec. PMID 25359724, Free PMC Article
    2. Drosophila expresses a CD98 transporter with an evolutionarily conserved structure and amino acid-transport properties. Reynolds B, et al. Biochem J, 2009 May 27. PMID 19335336, Free PMC Article
    3. Genome-wide analysis of promoter architecture in Drosophila melanogaster. Hoskins RA, et al. Genome Res, 2011 Feb. PMID 21177961, Free PMC Article
    4. SLC46 Family Transporters Facilitate Cytosolic Innate Immune Recognition of Monomeric Peptidoglycans. Paik D, et al. J Immunol, 2017 Jul 1. PMID 28539433, Free PMC Article
    5. Differential amino acid transporter expression in adult Drosophila melanogaster tissues. Wright Y, et al. MicroPubl Biol, 2024. PMID 38481556, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables L-amino acid transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables amino acid transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in amino acid transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in vacuolar membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG13384-PB
    CG13384-PC
    CG13384-PD
    CG13384-PE
    CG13384-PF
    CG13384-PG
    CG13384-PH
    CG13384-PI
    CG13384-PJ
    CG13384-PK
    CG13384-PL

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      8384455..8388804
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_164814.5 → NP_723385.1  uncharacterized protein Dmel_CG13384, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723385.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH21, Q7KTI1
      Related
      FBpp0079270
      Conserved Domains (2) summary
      COG0814
      Location:71 → 463
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:73 → 474
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    2. NM_001201794.2 → NP_001188723.1  uncharacterized protein Dmel_CG13384, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188723.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH21, Q7KTI1
      Conserved Domains (2) summary
      COG0814
      Location:71 → 463
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:73 → 474
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    3. NM_164815.5 → NP_723386.1  uncharacterized protein Dmel_CG13384, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723386.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH21, Q7KTI1
      Related
      FBpp0079272
      Conserved Domains (2) summary
      COG0814
      Location:71 → 463
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:73 → 474
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    4. NM_001201796.2 → NP_001188725.1  uncharacterized protein Dmel_CG13384, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188725.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH21, Q9VLM4
      Conserved Domains (2) summary
      COG0814
      Location:74 → 466
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:76 → 477
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    5. NM_205935.3 → NP_995657.1  uncharacterized protein Dmel_CG13384, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995657.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH21, Q7KTI1
      Conserved Domains (2) summary
      COG0814
      Location:71 → 463
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:73 → 474
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    6. NM_205936.3 → NP_995658.1  uncharacterized protein Dmel_CG13384, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_995658.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH21, Q8MSR2
      Conserved Domains (2) summary
      COG0814
      Location:70 → 462
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:72 → 473
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    7. NM_164812.5 → NP_723383.1  uncharacterized protein Dmel_CG13384, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723383.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH21, Q9VLM3
      Related
      FBpp0079271
      Conserved Domains (2) summary
      COG0814
      Location:92 → 484
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:94 → 495
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    8. NM_001201795.2 → NP_001188724.1  uncharacterized protein Dmel_CG13384, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188724.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH21, Q7KTI1
      Conserved Domains (2) summary
      COG0814
      Location:71 → 463
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:73 → 474
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    9. NM_001201797.2 → NP_001188726.1  uncharacterized protein Dmel_CG13384, isoform K [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188726.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH21, Q8MSR2
      Conserved Domains (2) summary
      COG0814
      Location:70 → 462
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:72 → 473
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    10. NM_164813.4 → NP_723384.1  uncharacterized protein Dmel_CG13384, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_723384.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH21, Q9VLM4
      Related
      FBpp0079273
      Conserved Domains (2) summary
      COG0814
      Location:74 → 466
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:76 → 477
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    11. NM_001201798.2 → NP_001188727.1  uncharacterized protein Dmel_CG13384, isoform L [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188727.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E8NH21, Q8MSR2
      Conserved Domains (2) summary
      COG0814
      Location:70 → 462
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:72 → 473
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7KTI1 Q7KTI1
    Q8MSR2 Q8MSR2
    Q9VLM3 Q9VLM3
    Q9VLM4 Q9VLM4

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