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    CG6891 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32865, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG6891provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030955
    Locus tag
    Dmel_CG6891
    See related
    AllianceGenome:FB:FBgn0030955
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Cotl1; Dmel\CG6891
    Summary
    Predicted to enable actin filament binding activity. Predicted to be involved in regulation of actin filament polymerization. Predicted to be active in cortical actin cytoskeleton and site of polarized growth. Predicted to colocalize with actin filament. Is expressed in several structures, including adult head; larval muscle cell; larval muscle system; posterior endoderm; and posterior midgut primordium. Orthologous to human COTL1 (coactosin like F-actin binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG6891 in Genome Data Viewer
    Location:
    17D4-17D5; 1-60 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (18775228..18781345)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (18669261..18675378)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Cholecystokinin-like receptor at 17D3 Neighboring gene uncharacterized protein Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene S6 Kinase Like Neighboring gene Autophagy-related 101

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in regulation of actin filament polymerization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    colocalizes_with actin filament IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cortical actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in site of polarized growth IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG6891-PA
    CG6891-PB
    CG6891-PC

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      18775228..18781345
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_133095.2NP_573323.1  uncharacterized protein Dmel_CG6891, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_573323.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VWQ7
      Related
      FBpp0074402
      Conserved Domains (1) summary
      cd11282
      Location:28139
      ADF_coactosin_like; Coactosin-like members of the ADF homology domain family
    2. NM_001272760.1NP_001259689.1  uncharacterized protein Dmel_CG6891, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001259689.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IQX5
      Conserved Domains (1) summary
      cd11282
      Location:11122
      ADF_coactosin_like; Coactosin-like members of the ADF homology domain family
    3. NM_167630.2NP_728196.1  uncharacterized protein Dmel_CG6891, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_728196.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IQX5
      Related
      FBpp0074403
      Conserved Domains (1) summary
      cd11282
      Location:11122
      ADF_coactosin_like; Coactosin-like members of the ADF homology domain family