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    Aldolase-type TIM barrel family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 828226, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Aldolase-type TIM barrel family protein
    Primary source
    TAIR:AT4G02610
    Locus tag
    AT4G02610
    See related
    Araport:AT4G02610
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T10P11.11; T10P11_11
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    8
    Sequence:
    Chromosome: 4; NC_003075.7 (1147608..1149336)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Seven transmembrane MLO family protein Neighboring gene vacuolar ATPase subunit F family protein Neighboring gene ncRNA Neighboring gene Protein kinase superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis indole synthase, a homolog of tryptophan synthase alpha, is an enzyme involved in the Trp-independent indole-containing metabolite biosynthesis. Zhang R, et al. J Integr Plant Biol, 2008 Sep. PMID 18844775
    2. Arabidopsis thaliana tryptophan synthase alpha: gene cloning, expression, and subunit interaction. Radwanski ER, et al. Mol Gen Genet, 1995 Oct 25. PMID 7476868
    3. Immunological characterization and chloroplast localization of the tryptophan biosynthetic enzymes of the flowering plant Arabidopsis thaliana. Zhao J, et al. J Biol Chem, 1995 Mar 17. PMID 7890741
    4. Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana. Mayer K, et al. Nature, 1999 Dec 16. PMID 10617198

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. INS catalyzes the conversion of indole-3-glycerol phosphate to indole and may be involved in the biosynthesis of Tryptophan-independent indole-3-acetic acid or other secondary metabolites in Arabidopsis. [INS]
      Title: Arabidopsis indole synthase, a homolog of tryptophan synthase alpha, is an enzyme involved in the Trp-independent indole-containing metabolite biosynthesis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    NM_116495.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables indole-3-glycerol-phosphate lyase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables tryptophan synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables tryptophan synthase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in tryptophan biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tryptophan biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Aldolase-type TIM barrel family protein
    NP_192170.1
    • Aldolase-type TIM barrel family protein; CONTAINS InterPro DOMAIN/s: Tryptophan synthase, alpha chain, active site (InterPro:IPR018204), Aldolase-type TIM barrel (InterPro:IPR013785), Ribulose-phosphate binding barrel (InterPro:IPR011060), Tryptophan synthase, alpha chain (InterPro:IPR002028); BEST Arabidopsis thaliana protein match is: tryptophan synthase alpha chain (TAIR:AT3G54640.1); Has 7706 Blast hits to 7706 proteins in 2293 species: Archae - 225; Bacteria - 4607; Metazoa - 6; Fungi - 175; Plants - 137; Viruses - 0; Other Eukaryotes - 2556 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      1147608..1149336
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116495.4 → NP_192170.1  Aldolase-type TIM barrel family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192170.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O22765, Q43290
      UniProtKB/TrEMBL
      A0A178UX50, A0A5S9XPM4, A0A654FL95
      Conserved Domains (1) summary
      PLN02591
      Location:25 → 273
      PLN02591; tryptophan synthase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O22765.2

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