GSTF2 glutathione S-transferase PHI 2 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: GSTF2
Official Full Name: glutathione S-transferase PHI 2
Primary source: TAIR:AT4G02520
Locus tag: AT4G02520
See related: Araport:AT4G02520
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATGSTF2; ATPM24; ATPM24.1; glutathione S-transferase PHI 2; GST2; T10P11.18; T10P11_18
Summary: Encodes glutathione transferase belonging to the phi class of GSTs. Naming convention according to Wagner et al. (2002). The expression of this gene is upregulated by herbicide safeners such as benoxacor and fenclorim.
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Genomic context

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See GSTF2 in Genome Data Viewer

Location:: chromosome: 4

Exon count:: 3

Sequence:: Chromosome: 4; NC_003075.7 (1110343..1112033, complement)

Chromosome 4 - NC_003075.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003075.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Homology

Orthologs from OrthoDB

NM_116486.3

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables camalexin binding	IDA Inferred from Direct Assay more info	PubMed
enables glutathione binding	IDA Inferred from Direct Assay more info	PubMed
enables glutathione transferase activity	IDA Inferred from Direct Assay more info	PubMed
enables quercitrin binding	IDA Inferred from Direct Assay more info	PubMed
enables salicylic acid binding	HDA more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within response to cadmium ion	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to cold	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to oomycetes	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to zinc ion	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within toxin catabolic process	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in apoplast	HDA more info	PubMed
located_in chloroplast	HDA more info	PubMed
located_in chloroplast stroma	HDA more info	PubMed
located_in cytoplasmic stress granule	IDA Inferred from Direct Assay more info	PubMed
located_in cytosol	HDA more info	PubMed
located_in intracellular membrane-bounded organelle	IDA Inferred from Direct Assay more info	PubMed
located_in plant-type vacuole	HDA more info	PubMed
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasmodesma	HDA more info	PubMed

General protein information

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Preferred Names: glutathione S-transferase PHI 2

NP_192161.1

glutathione S-transferase PHI 2 (GSTF2); FUNCTIONS IN: glutathione transferase activity, glutathione binding; INVOLVED IN: in 6 processes; LOCATED IN: in 7 components; EXPRESSED IN: phloem, cotyledon, root, cultured cell, leaf; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Glutathione S-transferase, C-terminal (InterPro:IPR004046), Glutathione S-transferase, C-terminal-like (InterPro:IPR010987), Glutathione S-transferase/chloride channel, C-terminal (InterPro:IPR017933), Glutathione S-transferase, N-terminal (InterPro:IPR004045), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: glutathione S-transferase F3 (TAIR:AT2G02930.1); Has 12309 Blast hits to 12301 proteins in 1354 species: Archae - 0; Bacteria - 6906; Metazoa - 1516; Fungi - 747; Plants - 1046; Viruses - 0; Other Eukaryotes - 2094 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003075.7 Reference assembly

Range

1110343..1112033 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_116486.3 → NP_192161.1 glutathione S-transferase PHI 2 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_192161.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P46422

UniProtKB/TrEMBL

A0A178V0A3, A0A5S9XP88, Q8LC43

Conserved Domains (2) summary

cd03187
Location:96 → 211

GST_C_Phi; C-terminal, alpha helical domain of Class Phi Glutathione S-transferases

cd03053
Location:4 → 78

GST_N_Phi; GST_N family, Class Phi subfamily; composed of plant-specific class Phi GSTs and related fungal and bacterial proteins. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide ...