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    Zfp784 zinc finger protein 784 [ Mus musculus (house mouse) ]

    Gene ID: 654801, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Zfp784provided by MGI
    Official Full Name
    zinc finger protein 784provided by MGI
    Primary source
    MGI:MGI:3606042
    See related
    Ensembl:ENSMUSG00000043290 AllianceGenome:MGI:3606042
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Znf784; C730049F21Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be active in nucleus. Orthologous to human ZNF784 (zinc finger protein 784). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 5.0), duodenum adult (RPKM 4.9) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Zfp784 in Genome Data Viewer
    Location:
    7 A1; 7 2.91 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (5037445..5041445, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (5034446..5038446, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_17950 Neighboring gene zinc finger protein 524 Neighboring gene STARR-positive B cell enhancer ABC_E4889 Neighboring gene zinc finger protein 865 Neighboring gene STARR-positive B cell enhancer ABC_E3696 Neighboring gene zinc finger protein 580 Neighboring gene STARR-positive B cell enhancer ABC_E4890 Neighboring gene predicted gene 15510 Neighboring gene coiled-coil domain containing 106

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Nagamachi A, et al. Cancer Cell, 2013 Sep 9. PMID 24029230
    2. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific double-stranded DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within hematopoietic progenitor cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 784

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039532.2 → NP_001034621.1  zinc finger protein 784

      See identical proteins and their annotated locations for NP_001034621.1

      Status: VALIDATED

      Source sequence(s)
      AK050452, BB620617
      Consensus CDS
      CCDS20755.1
      UniProtKB/Swiss-Prot
      Q8BI69
      UniProtKB/TrEMBL
      B2RVK6
      Related
      ENSMUSP00000051979.5, ENSMUST00000062428.5
      Conserved Domains (4) summary
      COG5048
      Location:193 → 297
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:197 → 217
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:251 → 273
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:209 → 234
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      5037445..5041445 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BI69.1 GenPept UniProtKB/Swiss-Prot:Q8BI69

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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