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    CPK13 calcium-dependent protein kinase 13 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 824348, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CPK13
    Official Full Name
    calcium-dependent protein kinase 13
    Primary source
    TAIR:AT3G51850
    Locus tag
    AT3G51850
    See related
    Araport:AT3G51850
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    calcium-dependent protein kinase 13
    Summary
    member of Calcium Dependent Protein Kinase
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    Genomic context

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    See CPK13 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Sequence:
    Chromosome: 3; NC_003074.8 (19232358..19235891)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene SAC domain-containing protein 8 Neighboring gene acyl-CoA oxidase 4 Neighboring gene cation exchanger 3 Neighboring gene Mitochondrial substrate carrier family protein Neighboring gene high mobility group B1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of Arabidopsis defense responses against Spodoptera littoralis by CPK-mediated calcium signaling. Kanchiswamy CN, et al. BMC Plant Biol, 2010 May 26. PMID 20504319, Free PMC Article
    2. CPK13, a noncanonical Ca2+-dependent protein kinase, specifically inhibits KAT2 and KAT1 shaker K+ channels and reduces stomatal opening. Ronzier E, et al. Plant Physiol, 2014 Sep. PMID 25037208, Free PMC Article
    3. Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system. Nemoto K, et al. Phytochemistry, 2011 Jul. PMID 21477822
    4. Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry. Nühse TS, et al. Mol Cell Proteomics, 2003 Nov. PMID 14506206
    5. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. reduces stomatal aperture through its inhibition of the guard cell-expressed KAT2 and KAT1 channels
      Title: CPK13, a noncanonical Ca2+-dependent protein kinase, specifically inhibits KAT2 and KAT1 shaker K+ channels and reduces stomatal opening.
    2. cpk3 and cpk13 mutants showed decreased transcript levels of defense genes in S. littoralis-damaged leaves.
      Title: Regulation of Arabidopsis defense responses against Spodoptera littoralis by CPK-mediated calcium signaling.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001339536.1
    NM_115044.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity HDA PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein autophosphorylation HDA PubMed 
    Component Evidence Code Pubs
    located_in cytosol HDA PubMed 
    located_in plasma membrane HDA PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    calcium-dependent protein kinase 13
    NP_190753.2
    • calcium-dependent protein kinase 13 (CPK13); FUNCTIONS IN: in 6 functions; INVOLVED IN: protein amino acid phosphorylation, N-terminal protein myristoylation; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), EF-Hand 1, calcium-binding site (InterPro:IPR018247), Serine/threonine-protein kinase domain (InterPro:IPR002290), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand-like domain (InterPro:IPR011992), EF-hand (InterPro:IPR018248), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), EF-HAND 2 (InterPro:IPR018249), Calcium-dependent protein kinase (InterPro:IPR020642), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: calcium-dependent protein kinase 30 (TAIR:AT1G74740.1); Has 124889 Blast hits to 118841 proteins in 3848 species: Archae - 180; Bacteria - 14009; Metazoa - 46910; Fungi - 16716; Plants - 24454; Viruses - 407; Other Eukaryotes - 22213 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      19232358..19235891
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001339535.1 → NP_001326349.1  calcium-dependent protein kinase 13 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LP02

    2. NM_115044.5 → NP_190753.2  calcium-dependent protein kinase 13 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190753.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q570G8, Q8W4I7, Q96294
      UniProtKB/TrEMBL
      A0A178VEY4, A0A5S9XK30
      Conserved Domains (4) summary
      COG5126
      Location:352 → 493
      FRQ1; Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms]
      cd05117
      Location:53 → 311
      STKc_CAMK; The catalytic domain of CAMK family Serine/Threonine Kinases
      cd15897
      Location:470 → 497
      EFh_PEF; EF-hand motif [structural motif]
      cl25352
      Location:470 → 526
      EFh_PEF; The penta-EF hand (PEF) family

    3. NM_001339536.1 → NP_001326348.1  calcium-dependent protein kinase 13 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1I9LP01
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8W4I7.2

    Gene LinkOut

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