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    VTI1B Vesicle transport v-SNARE family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839208, updated on 18-Sep-2024

    Summary

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    Official Symbol
    VTI1B
    Official Full Name
    Vesicle transport v-SNARE family protein
    Primary source
    TAIR:AT1G26670
    Locus tag
    AT1G26670
    See related
    Araport:AT1G26670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATVTI12; T24P13.5; T24P13_5; VESICAL TRANSPORT V-SNARE 12; VTI12
    Summary
    member of VTI1 Gene Family. Normally localizes to the transgolgi network and plasma membrane. A dominant mutation (zip1) alters the subcellular localization of VTI12 and suppresses loss of function mutation (zag1) of VTI11. Interacts with members of the SYP family. Involved in protein trafficking to protein storage vacuoles.
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    Genomic context

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    See VTI1B in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    5
    Sequence:
    Chromosome: 1; NC_003070.9 (9215770..9218010)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene Prefoldin chaperone subunit family protein Neighboring gene Mediator complex, subunit Med10 Neighboring gene transcriptional factor B3 family protein Neighboring gene emp24/gp25L/p24 family/GOLD family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conversion of functional specificity in Qb-SNARE VTI1 homologues of Arabidopsis. Niihama M, et al. Curr Biol, 2005 Mar 29. PMID 15797025
    2. Divergent functions of VTI12 and VTI11 in trafficking to storage and lytic vacuoles in Arabidopsis. Sanmartín M, et al. Proc Natl Acad Sci U S A, 2007 Feb 27. PMID 17360696, Free PMC Article
    3. Plasma membrane repair in plants. Schapire AL, et al. Trends Plant Sci, 2009 Dec. PMID 19819752
    4. NPSN11 is a cell plate-associated SNARE protein that interacts with the syntaxin KNOLLE. Zheng H, et al. Plant Physiol, 2002 Jun. PMID 12068098, Free PMC Article
    5. AtVPS45 is a positive regulator of the SYP41/SYP61/VTI12 SNARE complex involved in trafficking of vacuolar cargo. Zouhar J, et al. Plant Physiol, 2009 Apr. PMID 19251905, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Studies show that Ca2+ activates the SYT1-C2A domain, which, after binding to SNAREs, triggers vesicle-plasma-membrane fusion.
      Title: Plasma membrane repair in plants.
    2. A functional characterization of AtVPS45 (for vacuolar protein sorting 45), a protein from the Sec1/Munc18 family in Arabidopsis (Arabidopsis thaliana) that interacts at the trans-Golgi network (TGN) with the SYP41/SYP61/VTI12 SNARE complex, is reported.
      Title: AtVPS45 is a positive regulator of the SYP41/SYP61/VTI12 SNARE complex involved in trafficking of vacuolar cargo.
    3. Trafficking of VAC2 requires the SNARE VTI12 but not its close homologue, the conditionally redundant VTI11 protein.
      Title: Divergent functions of VTI12 and VTI11 in trafficking to storage and lytic vacuoles in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_102430.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables SNAP receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables SNARE binding TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables soluble NSF attachment protein activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within intra-Golgi vesicle-mediated transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within intracellular transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within_positive_effect protein storage vacuole organization IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within_positive_effect protein storage vacuole organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within protein targeting to vacuole IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in vesicle fusion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    part_of SNARE complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endosome HDA PubMed 
    located_in late endosome TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in trans-Golgi network HDA PubMed 
    located_in trans-Golgi network TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Vesicle transport v-SNARE family protein
    NP_564255.1
    • VTI1B; CONTAINS InterPro DOMAIN/s: Vesicle transport v-SNARE, N-terminal (InterPro:IPR007705); BEST Arabidopsis thaliana protein match is: Vesicle transport v-SNARE family protein (TAIR:AT5G39510.1); Has 841 Blast hits to 839 proteins in 213 species: Archae - 2; Bacteria - 11; Metazoa - 288; Fungi - 144; Plants - 215; Viruses - 0; Other Eukaryotes - 181 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      9215770..9218010
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102430.5 → NP_564255.1  Vesicle transport v-SNARE family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564255.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9LQY5, Q9SEL5
      UniProtKB/TrEMBL
      A0A178W140, A0A5S9W0W4
      Conserved Domains (2) summary
      cd15862
      Location:128 → 188
      SNARE_Vti1; SNARE motif of Vti1
      pfam05008
      Location:12 → 90
      V-SNARE; Vesicle transport v-SNARE protein N-terminus
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SEL5.3

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