Bpifb4 BPI fold containing family B, member 4 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Bpifb4provided by RGD
Official Full Name: BPI fold containing family B, member 4provided by RGD
Primary source: RGD:1561174
See related: EnsemblRapid:ENSRNOG00000034174 AllianceGenome:RGD:1561174
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RY2G5; Lplunc4
Summary: Predicted to enable lipid binding activity. Predicted to be located in actin cytoskeleton and cytosol. Orthologous to human BPIFB4 (BPI fold containing family B member 4). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 3.2), Thymus (RPKM 0.6) and 3 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 3q41

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	3	NC_086021.1 (162881478..162908207)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	3	NC_051338.1 (142423571..142448044)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	3	NC_005102.4 (149424392..149449350)

Chromosome 3 - NC_086021.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables lipid binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in actin cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in actin cytoskeleton	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in extracellular region	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: BPI fold-containing family B member 4

Names: ligand-binding protein RY2G5; long palate, lung and nasal epithelium carcinoma-associated protein 4; potential ligand-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001109209.2 → NP_001102679.2 BPI fold-containing family B member 4 precursor

See identical proteins and their annotated locations for NP_001102679.2

Status: VALIDATED

Source sequence(s)

JAXUCZ010000003

UniProtKB/Swiss-Prot

Q05704

UniProtKB/TrEMBL

A0A0H2UHZ5

Conserved Domains (2) summary

smart00329
Location:417 → 617

BPI2; BPI/LBP/CETP C-terminal domain

smart00328
Location:221 → 391

BPI1; BPI/LBP/CETP N-terminal domain