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    Cyp2c69 cytochrome P450, family 2, subfamily c, polypeptide 69 [ Mus musculus (house mouse) ]

    Gene ID: 100043108, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Cyp2c69provided by MGI
    Official Full Name
    cytochrome P450, family 2, subfamily c, polypeptide 69provided by MGI
    Primary source
    MGI:MGI:3721049
    See related
    Ensembl:ENSMUSG00000092008 AllianceGenome:MGI:3721049
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable arachidonate epoxygenase activity; heme binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Predicted to be involved in epoxygenase P450 pathway and xenobiotic metabolic process. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in liver adult (RPKM 247.6) and liver E18 (RPKM 141.3) See more
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    Genomic context

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    See Cyp2c69 in Genome Data Viewer
    Location:
    19 C3; 19 34.24 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (39831104..39875213, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (39842660..39886769, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 68 Neighboring gene STARR-seq mESC enhancer starr_46117 Neighboring gene STARR-seq mESC enhancer starr_46118 Neighboring gene STARR-seq mESC enhancer starr_46119 Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 40 Neighboring gene STARR-seq mESC enhancer starr_46120 Neighboring gene STARR-seq mESC enhancer starr_46121 Neighboring gene STARR-seq mESC enhancer starr_46122 Neighboring gene STARR-seq mESC enhancer starr_46123 Neighboring gene cytochrome P450, family 2, subfamily c, polypeptide 71, pseudogene Neighboring gene STARR-seq mESC enhancer starr_46124 Neighboring gene STARR-seq mESC enhancer starr_46125 Neighboring gene cytochrome P450, family 2. subfamily c, polypeptide 37

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables heme binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in organic acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in xenobiotic metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cytochrome P450, family 2, subfamily c, polypeptide 69

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001104525.1 → NP_001097995.1  cytochrome P450, family 2, subfamily c, polypeptide 69 precursor

      Status: PROVISIONAL

      Source sequence(s)
      AC148006
      Consensus CDS
      CCDS50432.1
      UniProtKB/TrEMBL
      E9PXC3, Q8VCP4
      Related
      ENSMUSP00000132832.2, ENSMUST00000168838.3
      Conserved Domains (1) summary
      pfam00067
      Location:30 → 487
      p450; Cytochrome P450

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      39831104..39875213 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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