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    rml-3 dTDP-4-dehydrorhamnose 3,5-epimerase [ Caenorhabditis elegans ]

    Gene ID: 180896, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rml-3
    Official Full Name
    dTDP-4-dehydrorhamnose 3,5-epimerase
    Primary source
    WormBase:WBGene00015781
    Locus tag
    CELE_C14F11.6
    See related
    AllianceGenome:WB:WBGene00015781
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable racemase and epimerase activity. Predicted to be involved in polysaccharide biosynthetic process. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rml-3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    5
    Sequence:
    Chromosome: X; NC_003284.9 (6238123..6239065, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene SHSP domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Aspartate aminotransferase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Acquired stress resilience through bacteria-to-nematode interdomain horizontal gene transfer. Pandey T, et al. EMBO J, 2023 Dec 11. PMID 37953666, Free PMC Article
    2. Isolation and molecular identification of nematode surface mutants with resistance to bacterial pathogens. O'Rourke D, et al. G3 (Bethesda), 2023 May 2. PMID 36911920, Free PMC Article
    3. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
    4. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article
    5. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables dTDP-4-dehydrorhamnose 3,5-epimerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables racemase and epimerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in polysaccharide biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    dTDP-4-dehydrorhamnose 3,5-epimerase
    NP_509046.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      6238123..6239065 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076645.5 → NP_509046.1  dTDP-4-dehydrorhamnose 3,5-epimerase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509046.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17993
      Conserved Domains (1) summary
      pfam00908
      Location:24 → 188
      dTDP_sugar_isom; dTDP-4-dehydrorhamnose 3,5-epimerase
    Nucleotide Protein
    Heading Accession and Version

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