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    txdc-15 Thioredoxin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 183759, updated on 9-Dec-2024

    Summary

    Official Symbol
    txdc-15
    Official Full Name
    Thioredoxin domain-containing protein
    Primary source
    WormBase:WBGene00008281
    Locus tag
    CELE_C53D6.4
    See related
    AllianceGenome:WB:WBGene00008281
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in cilium assembly. Predicted to be located in membrane. Predicted to be active in cilium. Human ortholog(s) of this gene implicated in Meckel syndrome. Orthologous to human TXNDC15 (thioredoxin domain containing 15). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See txdc-15 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    7
    Sequence:
    Chromosome: IV; NC_003282.8 (9019176..9020940, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene G_PROTEIN_RECEP_F1_2 domain-containing protein Neighboring gene Acetylcholine-gated chloride channel subunit acc-2 Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene pseudo

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cilium IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Thioredoxin domain-containing protein
    NP_001368463.1
    • Confirmed by transcript evidence
    NP_501568.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      9019176..9020940 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069167.5NP_501568.3  Thioredoxin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501568.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18810
      Conserved Domains (1) summary
      cl00388
      Location:118201
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
    2. NM_001380395.1NP_001368463.1  Thioredoxin domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      X5LXA5
      Conserved Domains (1) summary
      cl00388
      Location:22105
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold