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    tufm-2 Tr-type G domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172024, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tufm-2
    Official Full Name
    Tr-type G domain-containing protein
    Primary source
    WormBase:WBGene00007001
    Locus tag
    CELE_C43E11.4
    See related
    AllianceGenome:WB:WBGene00007001
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable translation elongation factor activity. Predicted to be involved in mitochondrial translational elongation. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tufm-2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (4247753..4249415)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Putative nudix hydrolase 7 Neighboring gene Exocyst complex component 7 Neighboring gene Conserved oligomeric Golgi complex subunit 5 Neighboring gene Transcription factor TFIIIC triple barrel domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of the residues involved in the unique serine specificity of Caenorhabditis elegans mitochondrial EF-Tu2. Sato A, et al. Biochemistry, 2006 Sep 12. PMID 16953577
    2. A unique tRNA recognition mechanism of Caenorhabditis elegans mitochondrial EF-Tu2. Suematsu T, et al. Nucleic Acids Res, 2005. PMID 16113240, Free PMC Article
    3. A unique serine-specific elongation factor Tu found in nematode mitochondria. Ohtsuki T, et al. Nat Struct Biol, 2002 Sep. PMID 12145639
    4. Characterization of the interaction between the nucleotide exchange factor EF-Ts from nematode mitochondria and elongation factor Tu. Ohtsuki T, et al. Nucleic Acids Res, 2002 Dec 15. PMID 12490713, Free PMC Article
    5. The chromatin factors SET-26 and HCF-1 oppose the histone deacetylase HDA-1 in longevity and gene regulation in C. elegans. Emerson FJ, et al. Nat Commun, 2024 Mar 14. PMID 38485937, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables translation elongation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables translation elongation factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translational elongation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in translational elongation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Tr-type G domain-containing protein
    NP_491338.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4247753..4249415
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058937.6 → NP_491338.2  Tr-type G domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491338.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EDF5
      Conserved Domains (1) summary
      PRK12736
      Location:43 → 423
      PRK12736; elongation factor Tu; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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