U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ador-1 G-protein coupled receptors family 1 profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174890, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ador-1
    Official Full Name
    G-protein coupled receptors family 1 profile domain-containing protein
    Primary source
    WormBase:WBGene00011878
    Locus tag
    CELE_T21B4.4
    See related
    AllianceGenome:WB:WBGene00011878
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to several human genes including ADORA1 (adenosine A1 receptor); ADORA2A (adenosine A2a receptor); and ADORA2B (adenosine A2b receptor). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ador-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    9
    Sequence:
    Chromosome: II; NC_003280.10 (12497212..12502884, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene C6 domain-containing protein Neighboring gene Serpentine Receptor, class H Neighboring gene Serpentine Receptor, class H

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Ilex paraguariensis modulates fat metabolism in Caenorhabditis elegans through purinergic system (ADOR-1) and nuclear hormone receptor (NHR-49) pathways. Machado ML, et al. PLoS One, 2018. PMID 30252861, Free PMC Article
    2. AdoR-1 (Adenosine Receptor) Contributes to Protection against Paraquat-Induced Oxidative Stress in Caenorhabditis elegans. Ling C, et al. Oxid Med Cell Longev, 2022. PMID 36589682, Free PMC Article
    3. High-throughput transcriptome sequencing reveals the protective role of adenosine receptor-related genes in paraquat-exposed Caenorhabditis elegans. Ma L, et al. Toxicol Res (Camb), 2023 Aug. PMID 37663816, Free PMC Article
    4. Mechanisms involved in anti-aging effects of guarana (Paullinia cupana) in Caenorhabditis elegans. Arantes LP, et al. Braz J Med Biol Res, 2018 Jul 2. PMID 29972429, Free PMC Article
    5. Cellular Expression and Functional Roles of All 26 Neurotransmitter GPCRs in the C. elegans Egg-Laying Circuit. Fernandez RW, et al. J Neurosci, 2020 Sep 23. PMID 32847964, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables neuropeptide Y receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    G-protein coupled receptors family 1 profile domain-containing protein
    NP_001040809.1
    • Confirmed by transcript evidence
    NP_001040810.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      12497212..12502884 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047345.5 → NP_001040810.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040810.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q1ZXT1
      Conserved Domains (1) summary
      cd14968
      Location:5 → 288
      7tmA_Adenosine_R; adenosine receptor subfamily, member of the class A family of seven-transmembrane G protein-coupled receptors

    2. NM_001047344.4 → NP_001040809.1  G-protein coupled receptors family 1 profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040809.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q1ZXT2
      Conserved Domains (2) summary
      cd14964
      Location:6 → 32
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:5 → 288
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.