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    C35A11.4 Major facilitator superfamily (MFS) profile domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178921, updated on 9-Dec-2024

    Summary

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    Official Symbol
    C35A11.4
    Official Full Name
    Major facilitator superfamily (MFS) profile domain-containing protein
    Primary source
    WormBase:WBGene00016431
    Locus tag
    CELE_C35A11.4
    See related
    AllianceGenome:WB:WBGene00016431
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable hexose transmembrane transporter activity. Predicted to be involved in monosaccharide transmembrane transport. Predicted to be active in membrane. Orthologous to several human genes including SLC2A11 (solute carrier family 2 member 11); SLC2A5 (solute carrier family 2 member 5); and SLC2A7 (solute carrier family 2 member 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See C35A11.4 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    11
    Sequence:
    Chromosome: V; NC_003283.11 (5389480..5393148, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hexose transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in hexose transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in monosaccharide transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Major facilitator superfamily (MFS) profile domain-containing protein
    NP_504430.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      5389480..5393148 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_072029.6 → NP_504430.2  Major facilitator superfamily (MFS) profile domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504430.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16547
      Conserved Domains (1) summary
      cd17357
      Location:13 → 461
      MFS_GLUT_Class1_2_like; Class 1 and Class 2 Glucose transporters (GLUTs) of the Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version

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