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    • Showing Current items.

    cyp-35B1 CYtochrome P450 family [ Caenorhabditis elegans ]

    Gene ID: 178803, updated on 9-Dec-2024

    Summary

    Official Symbol
    cyp-35B1
    Official Full Name
    CYtochrome P450 family
    Primary source
    WormBase:WBGene00019472
    Locus tag
    CELE_K07C6.4
    See related
    AllianceGenome:WB:WBGene00019472
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in organic acid metabolic process and xenobiotic metabolic process. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in hypodermal cell and intestine. Human ortholog(s) of this gene implicated in several diseases, including drug dependence (multiple); gastrointestinal system cancer (multiple); glucose metabolism disease (multiple); hypertension (multiple); and liver disease (multiple). Orthologous to several human genes including CYP2A13 (cytochrome P450 family 2 subfamily A member 13); CYP2A6 (cytochrome P450 family 2 subfamily A member 6); and CYP2A7 (cytochrome P450 family 2 subfamily A member 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cyp-35B1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (3939032..3941237)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene CYtochrome P450 family Neighboring gene ncRNA Neighboring gene CYtochrome P450 family Neighboring gene CYtochrome P450 family Neighboring gene ncRNA

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in organic acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in xenobiotic metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    CYtochrome P450 family
    NP_001309511.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      3939032..3941237
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001322546.2NP_001309511.1  CYtochrome P450 family [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44650
      Conserved Domains (1) summary
      pfam00067
      Location:26496
      p450; Cytochrome P450