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    rol-1 Nematode cuticle collagen N-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174857, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rol-1
    Official Full Name
    Nematode cuticle collagen N-terminal domain-containing protein
    Primary source
    WormBase:WBGene00004394
    Locus tag
    CELE_Y57A10A.11
    See related
    AllianceGenome:WB:WBGene00004394
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Predicted to be located in membrane. Predicted to be part of collagen trimer. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rol-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (12172573..12176069)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene SPK domain-containing protein Neighboring gene 3'-5' exonuclease domain-containing protein Neighboring gene ncRNA Neighboring gene LITAF domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Ancestral Caenorhabditis elegans Cuticle Suppresses rol-1. Noble LM, et al. G3 (Bethesda), 2020 Jul 7. PMID 32423919, Free PMC Article
    2. Molecular cloning of lin-29, a heterochronic gene required for the differentiation of hypodermal cells and the cessation of molting in C.elegans. Papp A, et al. Nucleic Acids Res, 1991 Feb 11. PMID 1672752, Free PMC Article
    3. LG II balancer chromosomes in Caenorhabditis elegans: mT1(II;III) and the mIn1 set of dominantly and recessively marked inversions. Edgley ML, et al. Mol Genet Genomics, 2001 Nov. PMID 11713668
    4. Genetic studies of unusual loci that affect body shape of the nematode Caenorhabditis elegans and may code for cuticle structural proteins. Kusch M, et al. Genetics, 1986 Jul. PMID 3732788, Free PMC Article
    5. The pie-1 and mex-1 genes and maternal control of blastomere identity in early C. elegans embryos. Mello CC, et al. Cell, 1992 Jul 10. PMID 1623520

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of collagen trimer IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nematode cuticle collagen N-terminal domain-containing protein
    NP_496589.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      12172573..12176069
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064188.6 → NP_496589.1  Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496589.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9NA83
      Conserved Domains (2) summary
      pfam01391
      Location:375 → 432
      Collagen; Collagen triple helix repeat (20 copies)
      smart01088
      Location:12 → 64
      Col_cuticle_N; Nematode cuticle collagen N-terminal domain
    Nucleotide Protein
    Heading Accession and Version

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