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    snpc-3.4 snRNA-activating protein complex subunit 3 [ Caenorhabditis elegans ]

    Gene ID: 192054, updated on 9-Dec-2024

    Summary

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    Official Symbol
    snpc-3.4
    Official Full Name
    snRNA-activating protein complex subunit 3
    Primary source
    WormBase:WBGene00011367
    Locus tag
    CELE_T02C12.2
    See related
    AllianceGenome:WB:WBGene00011367
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA polymerase III type 3 promoter sequence-specific DNA binding activity and bent DNA binding activity. Predicted to contribute to RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and core promoter sequence-specific DNA binding activity. Predicted to be involved in snRNA transcription by RNA polymerase II and snRNA transcription by RNA polymerase III. Predicted to be part of snRNA-activating protein complex. Orthologous to human SNAPC3 (small nuclear RNA activating complex polypeptide 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See snpc-3.4 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    8
    Sequence:
    Chromosome: III; NC_003281.10 (4020037..4021883)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Tubulin beta-2 chain Neighboring gene ncRNA Neighboring gene General transcription factor 3C polypeptide 5 Neighboring gene AAI domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The SNAPc complex mediates starvation-induced trans-splicing in Caenorhabditis elegans. Hou X, et al. J Genet Genomics, 2022 Oct. PMID 35283340
    2. The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans. Weng C, et al. Genes Dev, 2019 Jan 1. PMID 30567997, Free PMC Article
    3. A global analysis of genetic interactions in Caenorhabditis elegans. Byrne AB, et al. J Biol, 2007. PMID 17897480, Free PMC Article
    4. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    5. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    contributes_to RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase III type 3 promoter sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables bent DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to core promoter sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in snRNA transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in snRNA transcription by RNA polymerase III IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of snRNA-activating protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    snRNA-activating protein complex subunit 3
    NP_497807.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      4020037..4021883
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065406.6 → NP_497807.1  snRNA-activating protein complex subunit 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497807.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22092
      Conserved Domains (1) summary
      pfam12251
      Location:200 → 396
      zf-SNAP50_C; snRNA-activating protein of 50kDa MW C terminal
    Nucleotide Protein
    Heading Accession and Version

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