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    tric-1B.1 Trimeric intracellular cation channel type 1B.1 [ Caenorhabditis elegans ]

    Gene ID: 174867, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tric-1B.1
    Official Full Name
    Trimeric intracellular cation channel type 1B.1
    Primary source
    WormBase:WBGene00013255
    Locus tag
    CELE_Y57A10A.10
    See related
    AllianceGenome:WB:WBGene00013255
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable identical protein binding activity and potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human TMEM38A (transmembrane protein 38A). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tric-1B.1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (12256852..12266245, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene CAF1 family ribonuclease Neighboring gene Failed AXon Connections homolog;GST N-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene Armadillo repeat-containing protein 4

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pore architecture of TRIC channels and insights into their gating mechanism. Yang H, et al. Nature, 2016 Oct 27. PMID 27698420
    2. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
    3. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables identical protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in potassium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Trimeric intracellular cation channel type 1B.1
    NP_496603.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      12256852..12266245 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064202.4 → NP_496603.2  Trimeric intracellular cation channel type 1B.1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496603.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9NA75
      Conserved Domains (1) summary
      pfam05197
      Location:50 → 234
      TRIC; TRIC channel
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9NA75.2

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