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    F25H2.12 Methyltransferase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172945, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F25H2.12
    Official Full Name
    Methyltransferase domain-containing protein
    Primary source
    WormBase:WBGene00009123
    Locus tag
    CELE_F25H2.12
    See related
    AllianceGenome:WB:WBGene00009123
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable methyltransferase activity. Predicted to be involved in methylation. Located in striated muscle dense body. Orthologous to human METTL25B (methyltransferase like 25B). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F25H2.12 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    9
    Sequence:
    Chromosome: I; NC_003279.8 (10570079..10571920)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Large ribosomal subunit protein uL10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Translationally-controlled tumor protein homolog Neighboring gene Regulator of telomere elongation helicase 1 homolog Neighboring gene Glutaredoxin domain-containing protein;TCTP domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables methyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in striated muscle dense body HDA PubMed 

    General protein information

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    Preferred Names
    Methyltransferase domain-containing protein
    NP_492768.1
    • Confirmed by transcript evidence
    NP_871828.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      10570079..10571920
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_182028.5 → NP_871828.1  Methyltransferase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_871828.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8I4K4
      Conserved Domains (1) summary
      cl17173
      Location:89 → 240
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

    2. NM_060367.6 → NP_492768.1  Methyltransferase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492768.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q93574
      Conserved Domains (1) summary
      cl17173
      Location:127 → 278
      AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
    Nucleotide Protein
    Heading Accession and Version

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