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    prx-14 Peroxisomal membrane protein PEX14 [ Caenorhabditis elegans ]

    Gene ID: 178026, updated on 9-Dec-2024

    Summary

    Official Symbol
    prx-14
    Official Full Name
    Peroxisomal membrane protein PEX14
    Primary source
    WormBase:WBGene00004199
    Locus tag
    CELE_R07H5.1
    See related
    AllianceGenome:WB:WBGene00004199
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable signaling receptor binding activity. Predicted to be involved in protein import into peroxisome matrix, docking. Predicted to be located in membrane and peroxisome. Predicted to be part of peroxisomal importomer complex. Predicted to be active in peroxisomal membrane. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 13A. Orthologous to human PEX14 (peroxisomal biogenesis factor 14). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See prx-14 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    3
    Sequence:
    Chromosome: IV; NC_003282.8 (11183132..11184310)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene RAP homolog (vertebrate Rap GTPase family) Neighboring gene Uncharacterized protein Neighboring gene Calponin-homology (CH) domain-containing protein;Choline/carnitine acyltransferase domain-containing protein Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 Neighboring gene SKN-1 Dependent Zygotic transcript Neighboring gene F-box associated domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in protein import into peroxisome matrix, docking IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in peroxisomal membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in peroxisome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Peroxisomal membrane protein PEX14
    NP_502097.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11183132..11184310
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069696.5NP_502097.1  Peroxisomal membrane protein PEX14 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502097.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q93930
      Conserved Domains (1) summary
      pfam04695
      Location:1058
      Pex14_N; Peroxisomal membrane anchor protein (Pex14p) conserved region