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    Y41E3.7 ACB domain-containing protein;GOLD domain-containing protein;Golgi resident protein GCP60 [ Caenorhabditis elegans ]

    Gene ID: 178416, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y41E3.7
    Official Full Name
    ACB domain-containing protein;GOLD domain-containing protein;Golgi resident protein GCP60
    Primary source
    WormBase:WBGene00012765
    Locus tag
    CELE_Y41E3.7
    See related
    AllianceGenome:WB:WBGene00012765
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable fatty-acyl-CoA binding activity. Predicted to be active in Golgi membrane. Orthologous to human ACBD3 (acyl-CoA binding domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y41E3.7 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    11
    Sequence:
    Chromosome: IV; NC_003282.8 (15014035..15025514)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Glutaminyl-tRNA synthetase;Glutamyl/glutaminyl-tRNA synthetase class Ib anti-codon binding domain-containing protein;glutamine--tRNA ligase;putative glutamine--tRNA ligase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene FANCD2 Neighboring gene Glycine Rich Secreted Protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    2. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables fatty-acyl-CoA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ACB domain-containing protein;GOLD domain-containing protein;Golgi resident protein GCP60
    NP_001041026.1
    • Confirmed by transcript evidence
    NP_001041027.1
    • Confirmed by transcript evidence
    NP_001255846.1
    • Confirmed by transcript evidence
    NP_001294101.1
    • Confirmed by transcript evidence
    NP_001294234.1
    • Confirmed by transcript evidence
    NP_001368175.1
    • Partially confirmed by transcript evidence
    NP_001370058.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      15014035..15025514
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001307172.3 → NP_001294101.1  Golgi resident protein GCP60 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294101.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A078BQL1
      Conserved Domains (2) summary
      pfam00887
      Location:24 → 110
      ACBP; Acyl CoA binding protein
      pfam13897
      Location:293 → 447
      GOLD_2; Golgi-dynamics membrane-trafficking

    2. NM_001307305.3 → NP_001294234.1  ACB domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294234.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M1ZJ43
      Conserved Domains (1) summary
      cl00221
      Location:24 → 81
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...

    3. NM_001383252.2 → NP_001370058.1  Golgi resident protein GCP60 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62444
      Conserved Domains (2) summary
      pfam00887
      Location:24 → 110
      ACBP; Acyl CoA binding protein
      pfam13897
      Location:280 → 434
      GOLD_2; Golgi-dynamics membrane-trafficking

    4. NM_001047561.6 → NP_001041026.1  GOLD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041026.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2XMY1
      Conserved Domains (2) summary
      pfam13897
      Location:241 → 395
      GOLD_2; Golgi-dynamics membrane-trafficking
      cl00221
      Location:24 → 86
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...

    5. NM_001380546.1 → NP_001368175.1  GOLD domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      N1NV17
      Conserved Domains (1) summary
      pfam13897
      Location:196 → 350
      GOLD_2; Golgi-dynamics membrane-trafficking

    6. NM_001047562.4 → NP_001041027.1  GOLD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041027.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2EEM2
      Conserved Domains (2) summary
      pfam11498
      Location:31 → 131
      Activator_LAG-3; Transcriptional activator LAG-3
      pfam13897
      Location:183 → 337
      GOLD_2; Golgi-dynamics membrane-trafficking

    7. NM_001268917.3 → NP_001255846.1  GOLD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255846.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3YT98
      Conserved Domains (1) summary
      pfam13897
      Location:79 → 233
      GOLD_2; Golgi-dynamics membrane-trafficking
    Nucleotide Protein
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