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    Y55F3BR.2 BPTI/Kunitz inhibitor domain-containing protein;EB domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 190314, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y55F3BR.2
    Official Full Name
    BPTI/Kunitz inhibitor domain-containing protein;EB domain-containing protein
    Primary source
    WormBase:WBGene00021939
    Locus tag
    CELE_Y55F3BR.2
    See related
    AllianceGenome:WB:WBGene00021939
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y55F3BR.2 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    23
    Sequence:
    Chromosome: IV; NC_003282.8 (858930..874724)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Ankyrin repeat and LEM domain-containing protein 2 homolog Neighboring gene Ground-like domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ATP-dependent RNA helicase DDX1 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    BPTI/Kunitz inhibitor domain-containing protein;EB domain-containing protein
    NP_001294458.1
    • Confirmed by transcript evidence
    NP_001294459.1
    • Confirmed by transcript evidence
    NP_001294460.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      858930..874724
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001307529.2 → NP_001294458.1  BPTI/Kunitz inhibitor domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294458.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PMC3
      Conserved Domains (4) summary
      smart00131
      Location:649 → 703
      KU; BPTI/Kunitz family of serine protease inhibitors
      pfam00014
      Location:544 → 595
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam01683
      Location:1246 → 1297
      EB; EB module
      cl00101
      Location:756 → 813
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.

    2. NM_001307530.3 → NP_001294459.1  BPTI/Kunitz inhibitor domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294459.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PRM5
      Conserved Domains (4) summary
      smart00131
      Location:356 → 410
      KU; BPTI/Kunitz family of serine protease inhibitors
      pfam00014
      Location:251 → 302
      Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
      pfam01683
      Location:953 → 1004
      EB; EB module
      cl00101
      Location:463 → 520
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.

    3. NM_001307531.3 → NP_001294460.1  EB domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294460.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      U4PER8
      Conserved Domains (1) summary
      pfam01683
      Location:465 → 516
      EB; EB module
    Nucleotide Protein
    Heading Accession and Version

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